Sorting Nexin 6 (SNX6) (N-Term), (AA 81-110) antibody

Details for Product No. ABIN388255
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Antigen
Synonyms MGC75952, MGC80251, im:7146294, wu:fa55b10, zgc:110798, MSTP010, TFAF2, 2010006G21Rik, 2610032J07Rik, 2810425K19Rik, AU018928, C85963
Epitope
N-Term, AA 81-110
(9), (2), (1), (1), (1), (1), (1)
Reactivity
Human
(50), (14), (14), (12), (12), (12)
Host
Rabbit
(39), (11)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(4), (4), (4), (3), (3), (3), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(39), (24), (10), (3)
Pubmed 1 reference available
Quantity 400 μL
Options
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Catalog No. ABIN388255
291.50 $
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Immunogen This SNX6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 81-110 AA from the N-terminal region of human SNX6.
Clone RB12685
Isotype Ig
Specificity This SNX6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 88~118 amino acids from the N-terminal region of human SNX6.
Predicted Reactivity Mouse (Murine)
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name SNX6
Background SNX6 interacts with members of the transforming growth factor-beta family of receptor serine-threonine kinases. These receptors belong to two classes: type II receptors that bind ligand, and type I receptors that are subsequently recruited to transduce the signal. Of the type II receptors, SNX6 was found to interact strongly with ActRIIB and more moderately with wild type and kinase-defective mutants of TbetaRII. Of the type I receptors, SNX6 was found to interact only with inactivated TbetaRI. SNXs 1-4 also interacted with the transforming growth factor-beta receptor family, showing different receptor p
Synonyms: TRAF4-associated factor 2, Sorting nexin-6
Molecular Weight 46649 DA
Gene ID 58533
UniProt Q9UNH7
Research Area Stem Cells, Cell Cycle, Cell Structure
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-Sorting Nexin 6 (SNX6) (N-Term), (AA 81-110) antibody Western blot analysis of SNX6 Antibody (N-term) (ABIN388255) in HepG2 cell line lysates (35 µg/lane). SNX6 (arrow) was detected using the purified polyclonal antibody (1:60 dilution).
Background publications Parks, Frank, Huff et al.: "Sorting nexin 6, a novel SNX, interacts with the transforming growth factor-beta family of receptor serine-threonine kinases." in: The Journal of biological chemistry, Vol. 276, Issue 22, pp. 19332-9, 2001 (PubMed).

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