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DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 3, X-Linked (DDX3X) (AA 456-485), (C-Term) antibody

Details for Product No. ABIN388291, Supplier: Login to see
Antigen
  • DDX3X
  • DBX
  • DDX14
  • DDX3
  • HLP2
  • An3
  • pl10
  • Ddx3y
  • D1Pas1-rs2
  • Ddx3
  • Fin14
Epitope
AA 456-485, C-Term
22
19
16
6
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
Reactivity
Human
138
65
51
1
1
Host
Rabbit
127
11
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
4
4
4
2
2
2
2
2
2
2
2
2
2
2
2
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
108
58
46
27
25
22
20
15
5
4
3
2
1
1
1
1
Supplier
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Immunogen This DDX3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 456-485 AA from the C-terminal region of human DDX3.
Clone RB13438
Isotype Ig
Specificity This DDX3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 463~493 amino acids from the C-terminal region of human DDX3.
Predicted Reactivity Mouse (Murine),Xenopus laevis
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name DDX3 (DDX3X Antibody Abstract)
Background DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. DDX3 is a DEAD box protein, which interacts specifically with hepatitis C virus core protein resulting a change in intracellular location. The DDX3 gene has a homolog located in the nonrecombining region of the Y chromosome. The protein sequence is 91% identical between this gene and the Y-linked homolog.
Synonyms: DEAD box protein 3, X-chromosomal, Helicase-like protein 2, HLP2, DEAD box, X isoform, DDX3X, DBX
Molecular Weight 73113 DA
Gene ID 1654
UniProt O00571
Research Area Translation Factors, Stem Cells, Signaling, Chromatin
Pathways
Application Notes WB = 1:1000, IHC (p) = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 3, X-Linked (DDX3X) (AA 456-485), (C-Term) antibody (ABIN388291) Western blot analysis of DDX3 (arrow) using rabbit polyclonal DDX3 Antibody (C-term) ...
Western Blotting (WB) image for anti-DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 3, X-Linked (DDX3X) (AA 456-485), (C-Term) antibody (ABIN388291) Western blot analysis of DDX3 Antibody (C-term) (ABIN388291) in Hela cell line lysate...
Immunohistochemistry (IHC) image for anti-DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 3, X-Linked (DDX3X) (AA 456-485), (C-Term) antibody (ABIN388291) Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with DDX3 a...
Product cited in: Liang, Yang, Li et al.: "The Clinical and Pathological Significance of Nectin-2 and DDX3 Expression in Pancreatic Ductal Adenocarcinomas." in: Disease markers, Vol. 2015, pp. 379568, 2015 (PubMed).

Background publications Ariumi, Kuroki, Abe et al.: "DDX3 DEAD-box RNA helicase is required for hepatitis C virus RNA replication." in: Journal of virology, Vol. 81, Issue 24, pp. 13922-6, 2007 (PubMed).