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Details for Product No. ABIN388291

DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 3, X-Linked (DDX3X) (C-Term), (AA 456-485) antibody

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Antigen
Synonyms DBX, DDX3, HLP2, DDX14, Ddx3, Fin14, D1Pas1-rs2, An3, pl10, DDX3X
Epitope
»Alternatives C-Term, AA 456-485
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB), Immunohistochemistry (IHC)
Pubmed 1 reference available
Catalog no. ABIN388291
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen This DDX3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 456-485 AA from the C-terminal region of human DDX3.
Clone RB13438
Isotype Ig
Specificity This DDX3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 463~493 amino acids from the C-terminal region of human DDX3.
Predicted Reactivity Mouse (Murine),Xenopus laevis
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name DDX3
Background DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. DDX3 is a DEAD box protein, which interacts specifically with hepatitis C virus core protein resulting a change in intracellular location. The DDX3 gene has a homolog located in the nonrecombining region of the Y chromosome. The protein sequence is 91% identical between this gene and the Y-linked homolog.
Synonyms: DEAD box protein 3, X-chromosomal, Helicase-like protein 2, HLP2, DEAD box, X isoform, DDX3X, DBX
Molecular Weight 73113 DA
Gene ID 1654
UniProt O00571
Research Area Translation Factors, Stem Cells, Signaling, Chromatin
Application Notes Recommend dilutions: WB : 1:1000,IHC : 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Background publications Ariumi, Kuroki, Abe et al.: "DDX3 DEAD-box RNA helicase is required for hepatitis C virus RNA replication." in: Journal of virology, Vol. 81, Issue 24, pp. 13922-6, 2007 (PubMed).

Alternatives for antigen "DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 3, X-Linked (DDX3X)", type "Antibodies"
Hosts (95), (5)
Reactivities (98), (67), (52), (25), (25), (24), (13), (1), (1)
Applications (76), (50), (26), (23), (20), (15), (11), (10), (3), (1), (1)
Conjugates (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Epitopes (19), (16), (8), (7), (4), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
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