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CDK1 antibody (Cyclin-Dependent Kinase 1) (AA 1-29)

Details for Product anti-CDK1 Antibody No. ABIN388320, Supplier: Log in to see
Antigen
  • 5363
  • cdc
  • cdc-2
  • cdc2
  • Cdc2
  • CDC2
  • cdc2-a
  • Cdc2a
  • CDC2A
  • CDC2AAT
  • cdc2Dm
  • cdc2x1.1
  • cdc28a
  • CDC28A
  • CDCDm
  • Cdk-1
  • Cdk1
  • CDK1
  • cdk1
  • CDK1/CDC2
  • CDK2
  • CDKA1
  • CDKA;1
  • cell division control 2
  • CG5363
  • CYCLIN-DEPENDENT KINASE A;1
  • Dcdc2
  • dCdk1
  • Dmcdc2
  • Dm cdc2
  • DmCdc2
  • DmCdk1
  • Dmel\\CG5363
  • group 4
  • l(2)31Eh
  • p34
  • p34cdc2
  • P34CDC2
  • POL3
  • pold
  • PSTAIR
  • wu:fc30e01
  • xcdc2
  • zgc:92032
Alternatives
anti-Human CDK1 antibody for Immunocytochemistry
Epitope
AA 1-29, N-Term
96
69
45
32
32
28
20
19
18
15
14
14
14
14
14
8
7
6
5
5
5
4
4
4
4
3
3
3
3
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
608
255
226
28
25
23
17
10
9
5
5
5
4
4
2
2
1
1
1
1
1
1
1
1
1
1
1
Host
Rabbit
496
151
Clonality (Clone)
Polyclonal ()
Conjugate
This CDK1 antibody is un-conjugated
27
24
21
17
16
16
5
5
5
5
5
5
5
5
5
1
1
Application
Flow Cytometry (FACS), Western Blotting (WB)
519
242
162
98
92
73
56
38
32
14
10
10
7
6
6
2
1
1
1
Supplier
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Immunogen This CDC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-29 AA from the N-terminal region of human CDC2.
Clone RB13695
Isotype Ig
Specificity This CDC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 8~37 amino acids from the N-terminal region of human CDC2.
Predicted Reactivity Cow (Bovine),Chicken
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name CDC2 (CDK1 Antibody Abstract)
Background CDC2 is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control.
Synonyms: Cell division control protein 2 homolog, p34 protein kinase, Cyclin-dependent kinase 1, CDK1
Molecular Weight 34095 DA
Gene ID 983
UniProt P06493
Research Area Apoptosis/Necrosis, Stem Cells, Cell Cycle, Cell Structure
Pathways Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway
Application Notes WB = 1:1000, FACS = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-CDK1 antibody (Cyclin-Dependent Kinase 1) (AA 1-29) (ABIN388320) Western blot analysis of CDC2 Antibody (N-term) in 293 cell line lysates (35 µg/lane)...
Western Blotting (WB) image for anti-CDK1 antibody (Cyclin-Dependent Kinase 1) (AA 1-29) (ABIN388320) Western blot analysis of CDC2 (arrow) using rabbit polyclonal CDC2 Antibody (N-term) ...
Flow Cytometry (FACS) image for anti-CDK1 antibody (Cyclin-Dependent Kinase 1) (AA 1-29) (ABIN388320) Flow cytometric analysis of 293 cells using CDC2 Antibody (N-term)(bottom histogram) ...
Background publications Skoufias, Indorato, Lacroix, Panopoulos, Margolis: "Mitosis persists in the absence of Cdk1 activity when proteolysis or protein phosphatase activity is suppressed." in: The Journal of cell biology, Vol. 179, Issue 4, pp. 671-85, 2007