Cyclin-Dependent Kinase 1 (CDK1) (C-Term), (AA 213-241) antibody

Details for Product No. ABIN388321
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Antigen
Synonyms
CDC2, CDC28A, P34CDC2, Cdc2, Cdc2a, p34, cdc2, wu:fc30e01, zgc:92032, 5363, CDCDm, CDK1, CDK1/CDC2, CG5363, Cdk-1, Cdk1, Dcdc2, Dm cdc2, DmCdc2, DmCdk1, Dmcdc2, Dmel\\CG5363, cdc, cdc2Dm, cdk1,  ... show more
CDC2, CDC28A, P34CDC2, Cdc2, Cdc2a, p34, cdc2, wu:fc30e01, zgc:92032, 5363, CDCDm, CDK1, CDK1/CDC2, CG5363, Cdk-1, Cdk1, Dcdc2, Dm cdc2, DmCdc2, DmCdk1, Dmcdc2, Dmel\\CG5363, cdc, cdc2Dm, cdk1, dCdk1, group 4, l(2)31Eh, CDC2A, CDC2AAT, CDK2, CDKA1, CDKA;1, CYCLIN-DEPENDENT KINASE A;1, cell division control 2 show less
Epitope
C-Term, AA 213-241
(52), (51), (38), (28), (17), (16), (12), (6), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(421), (248), (237), (43), (38), (27), (26), (26), (15), (7), (5), (4), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Host
Rabbit
(342), (123)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(13), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (1), (1)
Application
Western Blotting (WB)
(377), (157), (121), (87), (63), (63), (60), (39), (21), (11), (11), (9), (3), (1), (1), (1), (1), (1), (1)
Pubmed 1 reference available
Catalog no. ABIN388321
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Immunogen This CDC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 213-241 AA from the C-terminal region of human CDC2.
Clone RB13685
Isotype Ig
Specificity This CDC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 220~249 amino acids from the C-terminal region of human CDC2.
Predicted Reactivity Mouse (Murine),Rat (Rattus),Xenopus laevis
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name CDC2
Background CDC2 is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of CDC2 is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control.
Synonyms: Cell division control protein 2 homolog, p34 protein kinase, Cyclin-dependent kinase 1, CDK1
Molecular Weight 34095 DA
Gene ID 983
UniProt P06493
Research Area Phospho-specific antibodies, Stem Cells, Protein Modifications, Cell Cycle, Cell Structure
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-Cyclin-Dependent Kinase 1 (CDK1) (C-Term), (AA 213-241) antibody Western blot analysis of CDC2 (arrow) using rabbit polyclonal CDC2 Antibody (C-term) (ABIN388321).293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the CDC2 gene (Lane 2) (Origene Technologies).
Background publications Skoufias, Indorato, Lacroix et al.: "Mitosis persists in the absence of Cdk1 activity when proteolysis or protein phosphatase activity is suppressed." in: The Journal of cell biology, Vol. 179, Issue 4, pp. 671-85, 2007 (PubMed).

Hosts (342), (123)
Reactivities (421), (248), (237), (43), (38), (27), (26), (26), (15), (7), (5), (4), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applications (377), (157), (121), (87), (63), (63), (60), (39), (21), (11), (11), (9), (3), (1), (1), (1), (1), (1), (1)
Conjugates (13), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (1), (1)
Epitopes (52), (51), (38), (28), (17), (16), (12), (6), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Validation Images
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