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Estrogen Receptor 2 (ER Beta) (ESR2) (AA 369-397), (Center) antibody

Details for Product No. ABIN388440, Supplier: Log in to see
Antigen
  • ER[b]1
  • zfER-beta1
  • zfER[b]1
  • erb
  • esrb
  • estrb
  • nr3a2
  • ERbeta
  • er-beta
  • esr-beta
  • ESR2
  • er
  • esr2
  • erb2
  • erb1
  • ER-beta
  • ER[b]
  • Estrb
  • ER-BETA
  • ESR-BETA
  • ESRB
  • ESTRB
  • Erb
  • NR3A2
  • Erb2
  • ERB
  • ERBETA
  • CERB
  • ERBeta2
  • erbeta
  • Esr2
Alternatives
anti-Human Estrogen Receptor 2 (ER Beta) antibody for Immunofluorescence
Epitope
AA 369-397, Center
65
33
25
21
18
18
17
15
13
13
13
11
8
6
6
5
5
4
3
3
3
3
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
311
96
81
9
9
8
8
4
2
2
1
1
Host
Rabbit
253
61
15
5
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
19
18
15
11
9
9
3
3
3
3
3
3
3
3
3
1
1
Application
Flow Cytometry (FACS), Western Blotting (WB)
238
131
43
35
35
34
23
13
11
10
8
4
3
3
3
1
Supplier
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Immunogen This ESR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 369-397 AA from the Central region of human ESR2.
Clone RB17812
Isotype Ig
Specificity This ESR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 376~405 amino acids from the Center region of human ESR2.
Predicted Reactivity Cow (Bovine),Chicken,Pig (Porcine),Rat (Rattus)
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name ESR2 (ESR2 Antibody Abstract)
Background ESR2 is a nuclear hormone receptor. The protein binds estrogens with an affinity similar to that of ESR1, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner.
Synonyms: Estrogen receptor beta, ER-beta, Nuclear receptor subfamily 3 group A member 2, NR3A2, ESTRB, ESR2
Molecular Weight 59216 DA
Gene ID 2100
UniProt Q92731
Research Area Transcription Factors, Signaling
Pathways Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway
Application Notes WB = 1:1000, FACS = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-Estrogen Receptor 2 (ER Beta) (ESR2) (AA 369-397), (Center) antibody (ABIN388440) Western blot analysis of ESR2 antibody (Center) (ABIN388440) in mouse spleen tissue l...
Immunohistochemistry (IHC) image for anti-Estrogen Receptor 2 (ER Beta) (ESR2) (AA 369-397), (Center) antibody (ABIN388440) Formalin-fixed and paraffin-embedded human testis tissue reacted with ESR2 Antibody (...
Immunohistochemistry (IHC) image for anti-Estrogen Receptor 2 (ER Beta) (ESR2) (AA 369-397), (Center) antibody (ABIN388440) Flow cytometric analysis of HepG2 cells using ESR2 Antibody (Center)(bottom histogram...
Product cited in: Bi, Yang, Yu et al.: "Pregnancy serum facilitates hepatitis E virus replication in vitro." in: The Journal of general virology, Vol. 96, Issue Pt 5, pp. 1055-61, 2015 (PubMed).

Background publications Bu, Kashireddy, Chang et al.: "ERBP, a novel estrogen receptor binding protein enhancing the activity of estrogen receptor." in: Biochemical and biophysical research communications, Vol. 317, Issue 1, pp. 54-9, 2004 (PubMed).

Caira, Antonson, Pelto-Huikko et al.: "Cloning and characterization of RAP250, a novel nuclear receptor coactivator." in: The Journal of biological chemistry, Vol. 275, Issue 8, pp. 5308-17, 2000 (PubMed).

Chen, Lin, Schiltz et al.: "Nuclear receptor coactivator ACTR is a novel histone acetyltransferase and forms a multimeric activation complex with P/CAF and CBP/p300." in: Cell, Vol. 90, Issue 3, pp. 569-80, 1997 (PubMed).