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Estrogen Receptor 2 (ER Beta) (ESR2) (AA 369-397), (Center) antibody

Details for Product No. ABIN388440
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Antigen
Synonyms CERB, ERB, ERBETA, ER-beta, Erb, ESRB, ESTRB, NR3A2, ER-BETA, ESR-BETA, Erb2, ERbeta, ER[b]1, zfER-beta1, zfER[b]1, erb, esrb, estrb, nr3a2, er-beta, esr-beta, ESR2, er, esr2, erb2, erb1, erbeta, Esr2
Epitope
AA 369-397, Center
(25), (21), (19), (19), (16), (11), (9), (8), (7), (6), (5), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(215), (90), (78), (26), (25), (13), (3), (1), (1), (1), (1)
Host
Rabbit
(197), (39), (5), (3)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(13), (11), (8), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (1), (1)
Application
Western Blotting (WB), Flow Cytometry (FACS)
(182), (88), (54), (40), (33), (32), (26), (21), (20), (7), (3), (2), (1), (1), (1)
Pubmed 3 references available
Quantity 400 µL
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Catalog No. ABIN388440
238.50 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen This ESR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 369-397 AA from the Central region of human ESR2.
Clone RB17812
Isotype Ig
Specificity This ESR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 376~405 amino acids from the Center region of human ESR2.
Predicted Reactivity Cow (Bovine),Chicken,Pig (Porcine),Rat (Rattus)
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name ESR2
Background ESR2 is a nuclear hormone receptor. The protein binds estrogens with an affinity similar to that of ESR1, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner.
Synonyms: Estrogen receptor beta, ER-beta, Nuclear receptor subfamily 3 group A member 2, NR3A2, ESTRB, ESR2
Molecular Weight 59216 DA
Gene ID 2100
UniProt Q92731
Research Area Transcription Factors, Signaling
Application Notes WB = 1:1000, FACS = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-Estrogen Receptor 2 (ER Beta) (ESR2) (AA 369-397), (Center) antibody Western blot analysis of ESR2 antibody (Center) (ABIN388440) in mouse spleen tissue lysates (35 µg/lane). ESR2 (arrow) was detected using the purified polyclonal antibody.
anti-Estrogen Receptor 2 (ER Beta) (ESR2) (AA 369-397), (Center) antibody (2) Formalin-fixed and paraffin-embedded human testis tissue reacted with ESR2 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.
anti-Estrogen Receptor 2 (ER Beta) (ESR2) (AA 369-397), (Center) antibody (3) Flow cytometric analysis of HepG2 cells using ESR2 Antibody (Center)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Background publications Chen, Lin, Schiltz et al.: "Nuclear receptor coactivator ACTR is a novel histone acetyltransferase and forms a multimeric activation complex with P/CAF and CBP/p300." in: Cell, Vol. 90, Issue 3, pp. 569-80, 1997 (PubMed).

Caira, Antonson, Pelto-Huikko et al.: "Cloning and characterization of RAP250, a novel nuclear receptor coactivator." in: The Journal of biological chemistry, Vol. 275, Issue 8, pp. 5308-17, 2000 (PubMed).

Bu, Kashireddy, Chang et al.: "ERBP, a novel estrogen receptor binding protein enhancing the activity of estrogen receptor." in: Biochemical and biophysical research communications, Vol. 317, Issue 1, pp. 54-9, 2004 (PubMed).

Hosts (197), (39), (5), (3)
Reactivities (215), (90), (78), (26), (25), (13), (3), (1), (1), (1), (1)
Applications (182), (88), (54), (40), (33), (32), (26), (21), (20), (7), (3), (2), (1), (1), (1)
Conjugates (13), (11), (8), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (1), (1)
Epitopes (25), (21), (19), (19), (16), (11), (9), (8), (7), (6), (5), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN388440
238.50 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Validation Images
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