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BMP4 antibody (Bone Morphogenetic Protein 4) (AA 5-34)

Details for Product anti-BMP4 Antibody No. ABIN388454, Supplier: Log in to see
Antigen
  • bmp-4
  • zbmp-4
  • zgc:100779
  • XBMP-4
  • bmp2b
  • bmp2b1
  • bmp4
  • ofc11
  • xbmp4
  • zyme
  • BMP4
  • bmp-2
  • bmp2
  • bmp2-4
  • cb670
  • zbmp-2
  • zbmp2
  • BMP2B
  • BMP2B1
  • MCOPS6
  • OFC11
  • ZYME
  • Bmp-4
  • Bmp2b
  • Bmp2b-1
  • Bmp2b1
  • BOMPR4A
  • BMP-4
Epitope
AA 5-34, N-Term
23
13
9
6
5
5
5
5
5
5
5
5
3
3
2
2
2
2
1
1
1
1
1
1
1
1
Reactivity
Human
141
47
47
15
12
9
8
7
3
3
1
1
1
1
1
1
1
1
1
Host
Rabbit
163
38
9
1
Clonality (Clone)
Polyclonal ()
Conjugate
This BMP4 antibody is un-conjugated
19
16
6
3
2
2
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
134
97
55
29
16
11
11
8
4
4
3
1
1
1
1
Supplier
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Immunogen This Bmp4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 5-34 AA from the N-terminal region of human Bmp4.
Clone RB01857
Isotype Ig
Specificity This Bmp4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 12~42 amino acids from the N-terminal region of human Bmp4.
Predicted Reactivity Cow (Bovine),Mouse (Murine),Rabbit
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name Bmp4 (BMP4 Antibody Abstract)
Background Bmp4 is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. This particular family member plays an important role in the onset of endochondral bone formation in humans, and a reduction in expression has been associated with a variety of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Alternative splicing in the 5' untranslated region of this gene has been described and three variants are described, all encoding an identical protein.
Molecular Weight 46555 DA
Gene ID 652
NCBI Accession NP_001193
Research Area Cell Signaling, Cell Cycle, Cell Structure
Application Notes WB = 1:1000, IHC (p) = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Immunohistochemistry (IHC) image for anti-BMP4 antibody (Bone Morphogenetic Protein 4) (AA 5-34) (ABIN388454) Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with Bmp4 an...
Western Blotting (WB) image for anti-BMP4 antibody (Bone Morphogenetic Protein 4) (AA 5-34) (ABIN388454) Bmp4 Antibody (G20) (ABIN388454) western blot analysis in MDA-MB435 cell line lysates...
Western Blotting (WB) image for anti-BMP4 antibody (Bone Morphogenetic Protein 4) (AA 5-34) (ABIN388454) Western blot analysis of Bmp4 (arrow) using rabbit polyclonal Bmp4 Antibody (G20) (AB...
Background publications Sorescu, Sykes, Weiss et al.: "Bone morphogenic protein 4 produced in endothelial cells by oscillatory shear stress stimulates an inflammatory response." in: The Journal of biological chemistry, Vol. 278, Issue 33, pp. 31128-35, 2003 (PubMed).

Chadwick, Wang, Li et al.: "Cytokines and BMP-4 promote hematopoietic differentiation of human embryonic stem cells." in: Blood, Vol. 102, Issue 3, pp. 906-15, 2003 (PubMed).