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Details for Product No. ABIN388564

GABA(A) Receptor-Associated Protein (GABARAP) (N-Term), (AA 1-30) antibody

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Antigen
Synonyms ATG8A, GABARAP-a, MM46, GABARAP
Epitope
»Alternatives N-Term, AA 1-30
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Immunofluorescence (IF), Western Blotting (WB), Immunohistochemistry (IHC)
Pubmed 2 references available
Catalog no. ABIN388564
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Immunogen This GABARAP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 AA from the N-terminal region of human GABARAP.
Clone RB11846
Isotype Ig
Specificity This GABARAP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1~31 amino acids from the N-terminal region of human GABARAP.
Predicted Reactivity Cow (Bovine),Mouse (Murine),Rat (Rattus),Rabbit
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name GABARAP
Background Gamma-aminobutyric acid A receptors [GABA(A) receptors] are ligand-gated chloride channels that mediate inhibitory neurotransmission. GABARAP is GABA(A) receptor-associated protein, which is highly positively charged in its N-terminus and shares sequence similarity with light chain-3 of microtubule-associated proteins 1A and 1B. This protein clusters neurotransmitter receptors by mediating interaction with the cytoskeleton.
Synonyms: Gamma-aminobutyric acid receptor-associated protein, GABA(A) receptor-associated protein, MM46, GABARAP, FLC3B,
Molecular Weight 13918 DA
Gene ID 11337
UniProt O95166
Research Area Autophagy, Cell Structure
Application Notes Recommend dilutions: IF : 1:10-50,WB : 1:1000,IHC : 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Background publications Knight, Harris, McAlister et al.: "The X-ray crystal structure and putative ligand-derived peptide binding properties of gamma-aminobutyric acid receptor type A receptor-associated protein." in: The Journal of biological chemistry, Vol. 277, Issue 7, pp. 5556-61, 2002 (PubMed).

Tanida, Tanida-Miyake, Komatsu et al.: "Human Apg3p/Aut1p homologue is an authentic E2 enzyme for multiple substrates, GATE-16, GABARAP, and MAP-LC3, and facilitates the conjugation of hApg12p to hApg5p." in: The Journal of biological chemistry, Vol. 277, Issue 16, pp. 13739-44, 2002 (PubMed).

Alternatives for antigen "GABA(A) Receptor-Associated Protein (GABARAP)", type "Antibodies"
Hosts (52), (7), (4)
Reactivities (58), (25), (23), (13), (13), (1), (1)
Applications (54), (21), (10), (8), (6), (6), (2), (1), (1)
Conjugates (3), (3), (3), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (15), (2), (2), (2), (1), (1)
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