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Retinoblastoma Binding Protein 4 (RBBP4) (N-Term) antibody
Alternatives Western Blotting (WB), ELISA
|4 references available|
|Quantity||400 µL (0.25 mg/ml)|
|Price||280.50 $ Plus shipping costs $45.00|
|Availability||Will be delivered in 2 to 3 Business Days|
|Immunogen||This RBBP4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human RBBP4.|
|Description||Other names: Chromatin assembly factor 1 subunit C, CAF-1 subunit C, Chromatin assembly factor I p48 subunit, CAF-I 48 kDa subunit, CAF-Ip48, Retinoblastoma binding protein p48, Retinoblastoma-binding protein 4, RBBP-4, MSI1 protein homolog, RBBP4, RBAP48,|
|Characteristics||Purified Rabbit Polyclonal Antibody (Pab)|
|Specificity||This RBBP4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human RBBP4.|
|Molecular Weight||47525 DA|
Background: RBBP4 is a ubiquitously expressed nuclear protein which belongs to a highly conserved subfamily of WD-repeat proteins. It is present in protein complexes involved in histone acetylation and chromatin assembly. It is part of the Mi-2 complex which has been implicated in chromatin remodeling and transcriptional repression associated with histone deacetylation. This encoded protein is also part of co-repressor complexes, which is an integral component of transcriptional silencing. It is found among several cellular proteins that bind directly to retinoblastoma protein to regulate cell proliferation. This protein also seems to be involved in transcriptional repression of E2F-responsive genes.
|Synonyms||NURF55, RBAP48, 154659_at, 55, caf-1, Caf-1, CAF-1, caf1, CAF1, caf1 p55, Caf1/p55, Caf1p55, CAF1p55, CG4236, d-CAF1, dCAF-1, dCAF-1 p55, DmelCG4236, dNURF, MSI1/RbAp48/CAC3/LIN-53, NURF, Nurf-55, NURF-55, Nurf55, p55, P55, p55/NURF-55, p55CAF1, RbAp48, nurf55, rbap48, MGC79922, mRbAp48, RBBP4, rbb4-2, zgc:55349, zgc:77854, wu:fb33a09, wu:fb40e10, MGC128413, RBBP-4, DKFZp469A0122|
|Application Notes||The suggested dilution is: ELISA~~1:1,000 Western blot~~1:50~100|
|Buffer||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.Preca|
|Research Area||Signaling, Stem Cells, Protein Modifications, Cell Cycle, Transcription Factors, Chromatin, Cell Structure|
|Restrictions||For Research Use only|
Zhang, Dufau: "Silencing of transcription of the human luteinizing hormone receptor gene by histone deacetylase-mSin3A complex." in: The Journal of biological chemistry, Vol. 277, Issue 36, pp. 33431-8, 2002 (PubMed).
Kuzmichev, Nishioka, Erdjument-Bromage et al.: "Histone methyltransferase activity associated with a human multiprotein complex containing the Enhancer of Zeste protein." in: Genes & development, Vol. 16, Issue 22, pp. 2893-905, 2002 (PubMed).
Hengstschläger, Rosner, Fountoulakis et al.: "Regulation of PCNA and CAF-1 expression by the two tuberous sclerosis gene products." in: Biochemical and biophysical research communications, Vol. 307, Issue 3, pp. 737-42, 2003 (PubMed).
Yao, Yang: "The metastasis-associated proteins 1 and 2 form distinct protein complexes with histone deacetylase activity." in: The Journal of biological chemistry, Vol. 278, Issue 43, pp. 42560-8, 2003 (PubMed).
|Hosts||Rabbit (34), Mouse (10), Goat (1)|
|Reactivities||Human (43), Rat (Rattus) (26), Mouse (Murine) (25), Chicken (18), Cow (Bovine) (1), Dog (Canine) (1)|
|Applications||Western Blotting (WB) (28), Immunofluorescence (IF) (23), ELISA (17), Immunoprecipitation (IP) (11), Immunohistochemistry (IHC) (8), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (6), Immunocytochemistry (ICC) (3), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Flow Cytometry (FACS) (2), Immunoelectron Microscopy (IEM) (1)|
|Conjugates||Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1)|
|Epitopes||AA 1-425 (6), N-Term (2), AA 1-50 (1)|