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EIF2B3 antibody (C-Term)
EIF2B3
Reactivity: Human
WB
Host: Rabbit
Polyclonal
RB8435
unconjugated
Product Details anti-EIF2B3 Antibody
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Target
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EIF2B3
(Eukaryotic Translation Initiation Factor 2B, Subunit 3 Gamma, 58kDa (EIF2B3))
Binding Specificity
All epitopes for EIF2B3 antibodies
AA 344-376, C-Term
Reactivity
All reactivities for EIF2B3 antibodies
Human
Host
All hosts for EIF2B3 antibodies
Rabbit
Clonality
All clonalities for EIF2B3 antibodies
Polyclonal
Conjugate
All conjugates for EIF2B3 antibodies
This EIF2B3 antibody is un-conjugated
Application
All applications for EIF2B3 antibodies
Western Blotting (WB)
Predicted Reactivity
Pr
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogen
This EIF2B3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 344-376 amino acids from the C-terminal region of human EIF2B3.
Clone
RB8435
Isotype
Ig Fraction
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Alternatives
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Application Details
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Application Notes
WB: 1:1000
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date
6 months
Target Details for EIF2B3
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Target
EIF2B3
(Eukaryotic Translation Initiation Factor 2B, Subunit 3 Gamma, 58kDa (EIF2B3))
Alternative Name
EIF2B3 (EIF2B3 Products )
Synonyms
zgc:56473 antibody, 1190002P15Rik antibody, EIF-2B antibody, EIF2Bgamma antibody, eukaryotic translation initiation factor 2B subunit gamma L homeolog antibody, eukaryotic translation initiation factor 2B, subunit 3 gamma antibody, eukaryotic translation initiation factor 2B subunit gamma antibody, eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa antibody, eukaryotic translation initiation factor 2B, subunit 3 antibody, eif2b3.L antibody, eif2b3 antibody, EIF2B3 antibody, Eif2b3 antibody
Background
EIF2B3 catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. Mutations in each of the five subunits of translation initiation factor eIF2B, including subunit 3, can cause leukoencephalopathy with vanishing white matter. EIF2B3 has also been identified as a cofactor of hepatitis C virus internal ribosome entry site-mediated translation.
Molecular Weight
50240
Gene ID
8891
NCBI Accession
NP_001160060 , NP_001248347 , NP_065098
UniProt
Q9NR50
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