Bone Morphogenetic Protein Receptor, Type IB (BMPR1B) (C-Term) antibody

Antigen: Bone Morphogenetic Protein Receptor, Type IB (BMPR1B)

Synonyms: ALK6, ALK-6, CDw293, Alk6, Acvrlk6, BMPR-IB, CFK-43a, AI385617, AV355320, alk6, alk-6, cdw293, MGC147272, alk6b, BR1b, alk6tr, zALK-6, MGC92220, zgc:92220, BMPR1B, RPK-1, BMP15, BMPRIB, FecB

Epitope: C-Term

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Certificates: ISO 9001:2008

Catalog no.: ABIN388739

Additional Information

Characteristics: Purified Rabbit Polyclonal Antibody (Pab)

Alternative name: BMPR1B (C-term)

Gene ID: 658

Swiss-Prot: NP_001194

Immunogen: This BMPR1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 473~502 amino acids from the C-terminal region of human BMPR1B.

Isotype: Ig  (Matching secondary antibodies)

Description: Other names: Serine(threonine) protein kinase, activin receptor-like kinase 6, ALK6

Specificity: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human BMPR1B.

Molecular Weight: 56930 DA

Application Details

Application Notes: The suggested dilution will be: ELISA~~1:1,000 Western blotting~~1:100~500 Immunohistochemistry~~1:50~100

Concentration: 0.25 mg/ml

Purification: Purified

Buffer: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Storage: Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles

Research Area: Phospho-specific antibodies, Stem Cells, Cell Signaling, Protein Modifications, Cell Structure

Restrictions: For Research Use only

Images

Western blot analysis of anti-BMPR1B Pab (ABIN388739) in NCI-H460 cell lysate. BMPR1B (arrow) was detected using purified Pab. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence.

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry. clinical relevance has not been evaluated. BC = breast carcinoma. HC = hepatocarcinoma.

Publications

Publications: Kan, Liu, McGuire et al.: "Dysregulation of local stem/progenitor cells as a common cellular mechanism for heterotopic ossification." in: Stem cells (Dayton, Ohio), Vol. 27, Issue 1, pp. 150-6, 2009 (PubMed).