Microtubule-Associated Protein tau (MAPT) (C-Term), (AA 677-707) antibody

Details for Product No. ABIN388782
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Antigen
Synonyms tau, xtp, MAPT, AI426939, AI551861, AW457082, CK1epsilon, CKIe, KC1epsilon, DDPAC, FTDP-17, MAPTL, MSTD, MTBT1, MTBT2, PPND, TAU, AI413597, AW045860, Mtapt, Tau, PHF-tau, RNPTAU, pTau
Epitope
C-Term, AA 677-707
(43), (33), (33), (30), (30), (30), (30), (26), (26), (26), (25), (25), (24), (23), (18), (13), (12), (11), (11), (11), (11), (10), (10), (10), (9), (9), (9), (8), (8), (8), (8), (8), (7), (5), (5), (5), (5), (5), (5), (5), (4), (4), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(859), (451), (428), (43), (8), (6), (3), (3), (2), (1), (1), (1), (1), (1)
Host
Rabbit
(801), (87), (10), (8), (1)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(10), (5), (3), (2), (2), (2), (1), (1)
Application
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
(795), (347), (237), (91), (75), (60), (31), (30), (16), (13), (13), (13), (9), (3), (1), (1)
Pubmed 4 references available
Quantity 400 µL
Options
Shipping to United States (Change)
Availability Will be delivered in 2 to 3 Business Days
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN388782
291.50 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen This TAU antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 677-707 AA from the C-terminal region of human TAU.
Clone RB2883
Isotype Ig
Specificity This TAU antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 685~714 amino acids from the C-terminal region of human TAU.
Predicted Reactivity Cow (Bovine),Mouse (Murine),Rat (Rattus)
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name tau
Background The microtubule-associated protein tau (MAPT) gene transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations result in several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.
Synonyms: Microtubule-associated protein tau, Neurofibrillary tangle protein, Paired helical filament-tau, PHF-tau, MAPT, MAPTL, MTBT1, TAU
Molecular Weight 78746 DA
Gene ID 4137
UniProt P10636
Research Area Stem Cells, Cell Structure, Neurology
Application Notes WB = 1:1000, IHC = 1:50-100, IF = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-Microtubule-Associated Protein tau (MAPT) (C-Term), (AA 677-707) antibody Western blot analysis of TAU(arrow) using rabbit polyclonal TAU Antibody (ABIN388782). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the TAU gene (Lane 2) (Origene Technologies).
anti-Microtubule-Associated Protein tau (MAPT) (C-Term), (AA 677-707) antibody (2) Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma
Background publications Kraemer, Zhang, Leverenz et al.: "Neurodegeneration and defective neurotransmission in a Caenorhabditis elegans model of tauopathy." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 17, pp. 9980-5, 2003 (PubMed).

Gamblin, Chen, Zambrano et al.: "Caspase cleavage of tau: linking amyloid and neurofibrillary tangles in Alzheimer's disease." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 17, pp. 10032-7, 2003 (PubMed).

Horiguchi, Uryu, Giasson et al.: "Nitration of tau protein is linked to neurodegeneration in tauopathies." in: The American journal of pathology, Vol. 163, Issue 3, pp. 1021-31, 2003 (PubMed).

Yoshiyama, Zhang, Bruce et al.: "Reduction of detyrosinated microtubules and Golgi fragmentation are linked to tau-induced degeneration in astrocytes." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 23, Issue 33, pp. 10662-71, 2003 (PubMed).

Validation Images
Did you look for something else?
back to top