TPX2 antibody (AA 350-382)

Catalog No. ABIN388785

Product Details anti-TPX2 Antibody

Target: TPX2 (TPX2, Microtubule-Associated, Homolog (Xenopus Laevis) (TPX2))

Binding Specificity: AA 350-382

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TPX2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This P100 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 350-382 amino acids from human P100.

Clone: RB0559

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for TPX2

Target: TPX2 (TPX2, Microtubule-Associated, Homolog (Xenopus Laevis) (TPX2))

Alternative Name: P100 (TPX2 Products)

Synonyms: C20orf1 antibody, C20orf2 antibody, DIL-2 antibody, DIL2 antibody, FLS353 antibody, GD:C20orf1 antibody, HCA519 antibody, HCTP4 antibody, REPP86 antibody, p100 antibody, 2610005B21Rik antibody, TPX2 antibody, dil-2 antibody, dil2 antibody, hctp4 antibody, repp86 antibody, tpx2 antibody, TPX2, microtubule nucleation factor antibody, TPX2, microtubule-associated antibody, TPX2, microtubule-associated, homolog (Xenopus laevis) antibody, TPX2, microtubule-associated S homeolog antibody, TPX2, microtubule-associated L homeolog antibody, TPX2 antibody, Tpx2 antibody, tpx2.S antibody, tpx2.L antibody

Background: The nuclear protein p100 is a proliferation-associated protein whose expression is restricted to cell cycle phases S, G2, and M. Exclusively expressed in proliferating cells from the transition G1/S until the end of cytokinesis. During mitosis it is strictly associated with the spindle pole and with the mitotic spindle, whereas during S and G2, it is diffusely distributed throughout the nucleus. The full-length cDNA encodes a 747-amino acid protein with a putative ATP/GTP-binding site motif. RT-PCR analysis demonstrated strong expression of in lung carcinoma cell lines but not in normal lung tissues. Expression was also found in adult placenta, skeletal muscle, thymus, testis, and small intestine and in fetal brain, liver, and kidney. P100 is also correlated to cancer prognosis.

Molecular Weight: 85653

Gene ID: 22974

NCBI Accession: NP_036244

UniProt: Q9ULW0