|+1 404 474 4654|
|+1 888 205 9894 (TF)|
Growth Differentiation Factor 15 (GDF15) (N-Term) antibody
|Synonyms||GDF15, PDF, MIC1, PLAB, MIC-1, NAG-1, PTGFB, GDF-15, SBF|
Alternatives Western Blotting (WB), ELISA
|3 references available|
|Quantity||400 µL (0.25 mg/ml) (Variants)|
|Price||280.50 $ Plus shipping costs $45.00|
|Availability||Will be delivered in 2 to 3 Business Days|
|Immunogen||This GDF15 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 23~52 amino acids from the N-terminal region of human GDF15.|
|Characteristics||Purified Rabbit Polyclonal Antibody (Pab)|
|Specificity||This GDF15 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 23~52 amino acids from the N-terminal region of human GDF15.|
|Molecular Weight||34168 DA|
Background: GDF15 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. GDF15 is highly expressed in placenta, with lower levels in prostate and colon and some expression in kidney.
|Application Notes||The suggested dilution is: ELISA~~1:1,000 Western blotting~~1:100~500 Immunohistochemistry ~~ 1:10~50|
|Buffer||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.Preca|
|Research Area||Stem Cells, Cell Signaling, Cell Structure|
|Restrictions||For Research Use only|
Bootcov, Bauskin, Valenzuela et al.: "MIC-1, a novel macrophage inhibitory cytokine, is a divergent member of the TGF-beta superfamily." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 94, Issue 21, pp. 11514-9, 1997 (PubMed).
Hromas, Hufford, Sutton et al.: "PLAB, a novel placental bone morphogenetic protein." in: Biochimica et biophysica acta, Vol. 1354, Issue 1, pp. 40-4, 1997 (PubMed).
Paralkar, Vail, Grasser et al.: "Cloning and characterization of a novel member of the transforming growth factor-beta/bone morphogenetic protein family." in: The Journal of biological chemistry, Vol. 273, Issue 22, pp. 13760-7, 1998 (PubMed).