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UCHL1 antibody (Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase)) (AA 187-214)

Details for Product anti-UCHL1 Antibody No. ABIN388870, Supplier: Log in to see
Antigen
  • AW822034
  • C88048
  • cb358
  • gad
  • MGC132191
  • park5
  • PARK5
  • PGP9.5
  • PGP 9.5
  • pgp9.5
  • PGP95
  • R75593
  • uch-l1
  • UCH-L1
  • Uch-L1
  • UCHL-1
  • UCHL1
  • uchl1
  • wu:fc55h08
Epitope
AA 187-214, C-Term
44
24
22
13
12
11
11
7
6
6
6
5
3
3
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Rat (Rattus)
310
104
93
27
21
11
7
7
4
4
4
3
3
1
1
Host
Rabbit
178
102
32
17
7
4
Clonality (Clone)
Polyclonal ()
Conjugate
This UCHL1 antibody is un-conjugated
12
12
9
7
7
7
1
1
1
1
1
1
1
1
1
Application
Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
256
126
89
55
46
15
13
11
10
8
6
3
3
Supplier
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Immunogen This UCHL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 187-214 AA from the C-terminal region of human UCHL1.
Clone RB21220
Isotype Ig
Specificity This UCHL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 193~223 amino acids from the C-terminal region of human UCHL1.
Predicted Reactivity Cow (Bovine),Mouse (Murine),Pig (Porcine),Monkey
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name UCHL1 (UCHL1 Antibody Abstract)
Background UCHL1 is a member of a gene family whose products hydrolyze small C-terminal adducts of ubiquitin to generate the ubiquitin monomer. Expression of UCHL1 is highly specific to neurons and to cells of the diffuse neuroendocrine system and their tumors. It is present in all neurons (Doran et al., 1983 [PubMed 6343558]).
Synonyms: Ubiquitin carboxyl-terminal hydrolase isozyme L1, UCH-L1, Ubiquitin thiolesterase L1, Neuron cytoplasmic protein 9.5, PGP 9.5, PGP9.5
Pathways: Parkinson's disease
Molecular Weight 24824 Da
Gene ID 7345
UniProt P09936
Research Area Ubiquitin-related antibodies, Cell Signaling, Protein Modifications, Neurology, Cell Structure
Application Notes WB = 1:1000, IF = 1:10-50, IHC (p) = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-UCHL1 antibody (Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase)) (AA 187-214) (ABIN388870) Western blot analysis of UCHL1 Antibody (C-term) (ABIN388870) in Ramos, NCI-H460 cell...
Western Blotting (WB) image for anti-UCHL1 antibody (Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase)) (AA 187-214) (ABIN388870) Western blot analysis of UCHL1 (arrow) using rabbit polyclonal UCHL1 Antibody (C-term...
Background publications Caballero, Resto, Patturajan, Meerzaman, Guo, Engles, Yochem, Ratovitski, Sidransky, Jen: "Interaction and colocalization of PGP9.5 with JAB1 and p27(Kip1)." in: Oncogene, Vol. 21, Issue 19, pp. 3003-10, 2002

Saigoh, Wang, Suh, Yamanishi, Sakai, Kiyosawa, Harada, Ichihara, Wakana, Kikuchi, Wada: "Intragenic deletion in the gene encoding ubiquitin carboxy-terminal hydrolase in gad mice." in: Nature genetics, Vol. 23, Issue 1, pp. 47-51, 1999