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USP11 antibody (N-Term)

USP11 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal RB4293-4294 unconjugated
Catalog No. ABIN388894
  • Target See all USP11 Antibodies
    USP11 (Ubiquitin Specific Peptidase 11 (USP11))
    Binding Specificity
    • 22
    • 7
    • 6
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    AA 279-308, N-Term
    Reactivity
    • 62
    • 13
    • 12
    • 1
    • 1
    Human
    Host
    • 56
    • 6
    • 1
    Rabbit
    Clonality
    • 47
    • 16
    Polyclonal
    Conjugate
    • 29
    • 6
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This USP11 antibody is un-conjugated
    Application
    • 42
    • 33
    • 27
    • 5
    • 4
    • 4
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This USP11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 279-308 amino acids from the N-terminal region of human USP11.
    Clone
    RB4293-4294
    Isotype
    Ig Fraction
    Top Product
    Discover our top product USP11 Primary Antibody
  • Application Notes
    WB: 1:1000. IHC-P: 1:50~100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Target
    USP11 (Ubiquitin Specific Peptidase 11 (USP11))
    Alternative Name
    USP11 (USP11 Products)
    Synonyms
    USP11 antibody, DKFZp459L098 antibody, UHX1 antibody, 6230415D12Rik antibody, mKIAA4085 antibody, Uhx1 antibody, ubiquitin specific peptidase 11 antibody, universal stress protein antibody, USP11 antibody, RR_RS19935 antibody, Usp11 antibody
    Background
    Modification of target proteins by ubiquitin participates in a wide array of biological functions. Proteins destined for degradation or processing via the 26 S proteasome are coupled to multiple copies of ubiquitin. However, attachment of ubiquitin or ubiquitin-related molecules may also result in changes in subcellular distribution or modification of protein activity. An additional level of ubiquitin regulation, deubiquitination, is catalyzed by proteases called deubiquitinating enzymes, which fall into four distinct families. Ubiquitin C-terminal hydrolases, ubiquitin-specific processing proteases (USPs),1 OTU-domain ubiquitin-aldehyde-binding proteins, and Jab1/Pad1/MPN-domain-containing metallo-enzymes. Among these four families, USPs represent the most widespread and represented deubiquitinating enzymes across evolution. USPs tend to release ubiquitin from a conjugated protein. They display similar catalytic domains containing conserved Cys and His boxes but divergent N-terminal and occasionally C-terminal extensions, which are thought to function in substrate recognition, subcellular localization, and protein-protein interactions.
    Molecular Weight
    109817
    Gene ID
    8237
    NCBI Accession
    NP_004642
    UniProt
    P51784
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