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LLGL1 antibody (Lethal Giant Larvae Homolog 1 (Drosophila)) (AA 172-205)

Details for Product anti-LLGL1 Antibody No. ABIN388988, Supplier: Login to see
Antigen
  • LLGL1
  • DLG4
  • HUGL
  • HUGL-1
  • HUGL1
  • LLGL
  • AI325176
  • Lgl1
  • Llglh
  • Mgl1
  • Rgl1
Alternatives
anti-Human LLGL1 antibody for Enzyme Immunoassay
Epitope
AA 172-205, N-Term
9
7
6
6
4
3
2
2
1
1
Reactivity
Human
22
6
4
Host
Rabbit
20
4
Clonality (Clone)
Polyclonal ()
Conjugate
This LLGL1 antibody is un-conjugated
1
1
1
1
1
1
1
Application
Western Blotting (WB)
22
14
2
2
1
1
Supplier
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Immunogen This LLGL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 172-205 AA from the N-terminal region of human LLGL1.
Clone RB7619
Isotype Ig
Specificity This LLGL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human LLGL1.
Predicted Reactivity Cow (Bovine),Mouse (Murine),Rat (Rattus)
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name LLGL1 (LLGL1 Antibody Abstract)
Background LLGL1 is a protein that is similar to a tumor suppressor in Drosophila. The protein is part of a cytoskeletal network and is associated with nonmuscle myosin II heavy chain and a kinase that specifically phosphorylates this protein at serine residues. The gene for LLGL1 is located within the Smith-Magenis syndrome region on chromosome 17.
Synonyms: Hugl protein, LLGL1, hugl,
Molecular Weight 114379 DA
Gene ID 3996
UniProt Q15334
Research Area Cancer, Signaling, Cell Structure
Pathways WNT Signaling
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-LLGL1 antibody (Lethal Giant Larvae Homolog 1 (Drosophila)) (AA 172-205) (ABIN388988) Western blot analysis of anti-hLLGL1 Pab (ABIN388988) in 293 cell line lysate. hLLGL1...
Background publications Schimanski, Schmitz, Kashyap et al.: "Reduced expression of Hugl-1, the human homologue of Drosophila tumour suppressor gene lgl, contributes to progression of colorectal cancer." in: Oncogene, Vol. 24, Issue 19, pp. 3100-9, 2005 (PubMed).

Grifoni, Garoia, Schimanski et al.: "The human protein Hugl-1 substitutes for Drosophila lethal giant larvae tumour suppressor function in vivo." in: Oncogene, Vol. 23, Issue 53, pp. 8688-94, 2004 (PubMed).

Katoh, Katoh: "Identification and characterization of human LLGL4 gene and mouse Llgl4 gene in silico." in: International journal of oncology, Vol. 24, Issue 3, pp. 737-42, 2004 (PubMed).