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FNTA antibody (AA 88-118)

FNTA Reactivity: Human, Mouse WB Host: Rabbit Polyclonal RB4792 unconjugated
Catalog No. ABIN389057
  • Target See all FNTA Antibodies
    FNTA (Farnesyltransferase, CAAX Box, alpha (FNTA))
    Binding Specificity
    • 8
    • 8
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 88-118
    Reactivity
    • 50
    • 25
    • 20
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 48
    • 2
    Rabbit
    Clonality
    • 49
    • 1
    Polyclonal
    Conjugate
    • 21
    • 4
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FNTA antibody is un-conjugated
    Application
    • 49
    • 22
    • 13
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Predicted Reactivity
    B, Rat
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This FNTA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 88-118 amino acids from the Central region of human FNTA.
    Clone
    RB4792
    Isotype
    Ig Fraction
    Top Product
    Discover our top product FNTA Primary Antibody
  • Application Notes
    WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Target
    FNTA (Farnesyltransferase, CAAX Box, alpha (FNTA))
    Alternative Name
    FNTA (FNTA Products)
    Synonyms
    ATFTA antibody, FARNESYLTRANSFERASE A antibody, FARNESYLTRANSFERASE SUBUNIT A antibody, PFT/PGGT-IALPHA antibody, PLP antibody, PLURIPETALA antibody, farnesyltransferase A antibody, FPTA antibody, PGGT1A antibody, PTAR2 antibody, PFAS antibody, FTA antibody, farnesyltransferase A antibody, farnesyltransferase, CAAX box, alpha antibody, FTA antibody, FNTA antibody, Fnta antibody
    Background
    FNTA, also known as CAAX farnesyltransferase (FTase), attaches a farnesyl group from farnesyl pyrophosphate to cysteine residues at the fourth position from the C terminus of proteins that end in the so-called CAAX box, where C is cysteine, A is usually but not always an aliphatic amino acid, and X is typically methionine or serine. This type of posttranslational modification provides a mechanism for membrane localization of proteins that lack a transmembrane domain. This enzyme has the remarkable property of farnesylating peptides as short as four residues in length that conform to the CAAX consensus sequence. FNTA is also a specific cytoplasmic interactor of the transforming growth factor-beta and activin type I receptors. It is likely to be a key component of the signaling pathway which involves p21ras, an important substrate for farnesyltransferase.
    Molecular Weight
    44409
    Gene ID
    2339
    NCBI Accession
    NP_002018
    UniProt
    P49354
    Pathways
    Response to Water Deprivation, Regulation of G-Protein Coupled Receptor Protein Signaling
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