Aryl Hydrocarbon Receptor Nuclear Translocator 2 (ARNT2) antibody

Antigen: Aryl Hydrocarbon Receptor Nuclear Translocator 2 (ARNT2)

Synonyms: Hif-2b, bHLHe1, mKIAA0307, KIAA0307, Arnt, arnt2X, arnt2a, zfARNT2, zfARNT2a, zfARNT2b, zfARNT2c, chunp6921, arnt2, MGC53123, arnt.2, MGC68805, ARNT2

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Certificates: ISO 9001:2008

Catalog no.: ABIN389076

Additional Information

Characteristics: Purified Rabbit Polyclonal Antibody (Pab)

Alternative name: ARNT /ARNT2

Gene ID: 9915

Swiss-Prot: Q9HBZ2

Immunogen: This ARNT /ARNT2 antibody is generated from rabbits immunized with the KLH conjugated synthetic peptide KTGTVKKEGQQSSMRCA containing a predicted sumoylation site from the N-terminal region of human ARNT and ARNT2.

Isotype: Ig  (Matching secondary antibodies)

Description: Other names: Aryl hydrocarbon receptor nuclear translocator, ARNT protein, Dioxin receptor, nuclear translocator, Hypoxia-inducible factor 1 beta, HIF-1 beta

Specificity: This antibody is generated from rabbits immunized with the KLH conjugated synthetic peptide KTGTVKKEGQQSSMRCA containing a predicted sumoylation site from the N-terminal region of human ARNT and ARNT2.

Molecular Weight: 77612 DA

Application Details

Application Notes: The suggested dilution is: ELISA~~1:1,000 Immunohistochemistry~~1:50~100 Western Blot~~ 1:250~500

Concentration: 0.25 mg/ml

Purification: Purified

Buffer: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Storage: Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles

Research Area: Cell Signaling, Protein Modifications, Cancer, Transcription Factors, Signaling, Neurology, Metabolism, Cell Structure

Restrictions: For Research Use only

Images

Western blot analysis of ARNT2 polyclonal antibody (ABIN389076) in K562 cell line lysates. Non-sumoylated ARNT2 (arrow) was detected using the purified Pab.

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry. clinical relevance has not been evaluated. BC = breast carcinoma. HC = hepatocarcinoma.