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SULT1A1 antibody (AA 128-160)

SULT1A1 Reactivity: Human, Mouse WB Host: Rabbit Polyclonal RB05112 unconjugated
Catalog No. ABIN389136
  • Target See all SULT1A1 Antibodies
    SULT1A1 (Sulfotransferase Family, Cytosolic, 1A, Phenol-Preferring, Member 1 (SULT1A1))
    Binding Specificity
    • 6
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 128-160
    Reactivity
    • 35
    • 19
    • 13
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 31
    • 8
    Rabbit
    Clonality
    • 33
    • 6
    Polyclonal
    Conjugate
    • 27
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SULT1A1 antibody is un-conjugated
    Application
    • 31
    • 14
    • 11
    • 8
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Predicted Reactivity
    Pr
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This SULT1A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 128-160 amino acids from the Central region of human SULT1A1.
    Clone
    RB05112
    Isotype
    Ig Fraction
    Top Product
    Discover our top product SULT1A1 Primary Antibody
  • Application Notes
    WB: 1:1000. WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Target
    SULT1A1 (Sulfotransferase Family, Cytosolic, 1A, Phenol-Preferring, Member 1 (SULT1A1))
    Alternative Name
    SULT1A1 (SULT1A1 Products)
    Synonyms
    HAST1/HAST2 antibody, P-PST antibody, PST antibody, ST1A1 antibody, ST1A3 antibody, STP antibody, STP1 antibody, TSPST1 antibody, AI266890 antibody, Stp antibody, Stp1 antibody, ASTIV antibody, Mx-ST antibody, PST-1 antibody, St1a1 antibody, Stm antibody, Sult1a3 antibody, pst antibody, st1a3 antibody, stp antibody, stp1 antibody, tspst1 antibody, cSULT1A1 antibody, SULT1A2 antibody, SULT1A1 antibody, SIAT8-D antibody, ST8SiaIV antibody, Siat8d antibody, PST1 antibody, SIAT8D antibody, ST8SIA-IV antibody, sulfotransferase family 1A member 1 antibody, sulfotransferase family 1A, phenol-preferring, member 1 antibody, sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 antibody, sulfotransferase family 1A member 1 S homeolog antibody, sulfotransferase 1A1 antibody, ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 antibody, SULT1A1 antibody, Sult1a1 antibody, sult1a1 antibody, sult1a1.S antibody, LOC704658 antibody, LOC709318 antibody, St8sia4 antibody, ST8SIA4 antibody, LOC100064221 antibody
    Background
    Sulphation is a significant detoxification pathway for diverse xenobiotics, yet this modification also plays an important role in the metabolism and bioactivation of many dietary and environmental mutagens, including heterocyclic amines implicated in the pathogenesis of several cancers. A major human sulfotransferase, SULT1A1, metabolizes and/or bioactivates many endogenous compounds and is implicated in a range of cancers because of its ability to transform xenobiotics to cellular mutagens and carcinogens. Genetic polymorphisms in human sulfotransferase 1A1 SULT1A1 have a major impact on SULT1A1 enzyme activity and affect the risk for cancer development in humans. A G--->A transition at codon 213 (CGC/Arg to CAC/His) of the SULT1A1 gene has been identified (SULT1A1*2), and individuals homozygous for the His allele have a markedly lower activity and stability of this enzyme than those with the high activity SULT1A1*1 allozyme, which has been associated with protection against dietary toxins and reduced susceptibility to colorectal and breast cancers.There is an increasing incidence of SULT1A1*1 homozygosity and decreasing incidence of SULT1A1*2 homozygosity with increasing age, indicating a potential association of SULT1A1*1 allozyme(s) with protection against cell and/or tissue damage during aging. CLN3, the locus for Batten disease, maps to the same region 16p12.1-p11.2 as SULT12A1, making SULT1A1 a candidate gene for this disorder.
    Molecular Weight
    34165
    Gene ID
    6817
    NCBI Accession
    NP_001046, NP_803565, NP_803566, NP_803878, NP_803880
    UniProt
    P50225
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