SMC2 antibody (C-Term)

Catalog No. ABIN389143

Product Details anti-SMC2 Antibody

Target: SMC2 (Structural Maintenance of Chromosomes 2 (SMC2))

Binding Specificity: AA 1166-1197, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SMC2 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This SMC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1166-1197 amino acids from the C-terminal region of human SMC2.

Clone: RB14711

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for SMC2

Target: SMC2 (Structural Maintenance of Chromosomes 2 (SMC2))

Alternative Name: SMC2 (SMC2 Products)

Synonyms: CAP-E antibody, CAPE antibody, SMC-2 antibody, SMC2L1 antibody, 5730502P04Rik antibody, AI255214 antibody, AW545314 antibody, Fin16 antibody, Smc2l1 antibody, fb92e05 antibody, wu:fb92e05 antibody, zeh1628 antibody, zgc:55326 antibody, xcap-e antibody, SCII antibody, structural maintenance of chromosomes 2 antibody, structural maintenance of chromosomes 2 L homeolog antibody, SMC2 antibody, Smc2 antibody, smc2 antibody, smc2.L antibody

Background: SMC2 is a central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.

Molecular Weight: 135656

Gene ID: 10592

NCBI Accession: NP_001036015, NP_001036016, NP_001252531, NP_006435

UniProt: O95347