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EOMES antibody (Eomesodermin) (AA 26-57)

Details for Product anti-EOMES Antibody No. ABIN389151, Supplier: Log in to see
Antigen
  • C77258
  • eom
  • EOMES
  • eomes
  • TBR-2
  • Tbr2
  • tbr2
  • TBR2
  • xeomes
Epitope
AA 26-57, N-Term
41
18
10
6
6
5
3
2
2
2
1
1
1
1
1
Reactivity
Human
84
20
2
2
1
Host
Rabbit
57
25
9
3
2
Clonality (Clone)
Polyclonal ()
Conjugate
This EOMES antibody is un-conjugated
6
5
5
4
4
4
2
2
2
2
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
67
45
26
12
4
4
3
2
1
1
1
Supplier
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Immunogen This EOMES (TBR2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 26-57 AA from the N-terminal region of human EOMES (TBR2).
Clone RB10349
Isotype Ig
Specificity This EOMES (TBR2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 34~64 amino acids from the N-terminal region of human EOMES.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name EOMES (TBR2) (EOMES Antibody Abstract)
Background This protein is a member of a conserved protein family that shares a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. A similiar protein disrupted in mice is shown to be essential during trophoblast development and gastrulation.
Synonyms: Eomesodermin homolog, EOMES, TBR2
Molecular Weight 72613 DA
Gene ID 8320
UniProt O95936
Research Area Stem Cells
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.43 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-EOMES antibody (Eomesodermin) (AA 26-57) (ABIN389151) Western blot analysis of EOMES (arrow) using rabbit polyclonal EOMES Antibody (Human ...
Background publications Baala, Briault, Etchevers, Laumonnier, Natiq, Amiel, Boddaert, Picard, Sbiti, Asermouh, Attié-Bitach, Encha-Razavi, Munnich, Sefiani, Lyonnet: "Homozygous silencing of T-box transcription factor EOMES leads to microcephaly with polymicrogyria and corpus callosum agenesis." in: Nature genetics, Vol. 39, Issue 4, pp. 454-6, 2007 (PubMed).

Intlekofer, Takemoto, Wherry, Longworth, Northrup, Palanivel, Mullen, Gasink, Kaech, Miller, Gapin, Ryan, Russ, Lindsten, Orange, Goldrath, Ahmed, Reiner: "Effector and memory CD8+ T cell fate coupled by T-bet and eomesodermin." in: Nature immunology, Vol. 6, Issue 12, pp. 1236-44, 2005 (PubMed).

Kimura, Nakashima, Ueno, Kiyama, Taga: "A novel mammalian T-box-containing gene, Tbr2, expressed in mouse developing brain." in: Brain research. Developmental brain research, Vol. 115, Issue 2, pp. 183-93, 1999 (PubMed).