Eomesodermin (EOMES) (N-Term), (AA 26-57) antibody

Details for Product No. ABIN389151
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Antigen
Synonyms EOMES, tbr2, xeomes, eom, eomes, TBR2, C77258, TBR-2, Tbr2
Epitope
N-Term, AA 26-57
(24), (9), (4), (2), (2), (2), (1), (1), (1), (1), (1)
Reactivity
Human
(56), (23), (15), (13), (12), (2)
Host
Rabbit
(47), (7), (2), (2), (1)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(49), (27), (10), (6), (4), (3), (1), (1), (1)
Pubmed 3 references available
Quantity 400 μL
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Catalog No. ABIN389151
291.50 $
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Immunogen This EOMES (TBR2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 26-57 AA from the N-terminal region of human EOMES (TBR2).
Clone RB10349
Isotype Ig
Specificity This EOMES (TBR2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 34~64 amino acids from the N-terminal region of human EOMES.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name EOMES (TBR2)
Background This protein is a member of a conserved protein family that shares a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. A similiar protein disrupted in mice is shown to be essential during trophoblast development and gastrulation.
Synonyms: Eomesodermin homolog, EOMES, TBR2
Molecular Weight 72613 DA
Gene ID 8320
UniProt O95936
Research Area Stem Cells
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.43 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-Eomesodermin (EOMES) (N-Term), (AA 26-57) antibody Western blot analysis of EOMES (arrow) using rabbit polyclonal EOMES Antibody (Human N-term) (ABIN389151). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the EOMES gene (Lane 2) (Origene Technologies).
Background publications Kimura, Nakashima, Ueno et al.: "A novel mammalian T-box-containing gene, Tbr2, expressed in mouse developing brain." in: Brain research. Developmental brain research, Vol. 115, Issue 2, pp. 183-93, 1999 (PubMed).

Intlekofer, Takemoto, Wherry et al.: "Effector and memory CD8+ T cell fate coupled by T-bet and eomesodermin." in: Nature immunology, Vol. 6, Issue 12, pp. 1236-44, 2005 (PubMed).

Baala, Briault, Etchevers et al.: "Homozygous silencing of T-box transcription factor EOMES leads to microcephaly with polymicrogyria and corpus callosum agenesis." in: Nature genetics, Vol. 39, Issue 4, pp. 454-6, 2007 (PubMed).

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