Eomesodermin (EOMES) (N-Term), (AA 26-57) antibody

Details for Product No. ABIN389151
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Antigen
Synonyms TBR2, xeomes, EOMES, tbr2, eom, eomes
Epitope
N-Term, AA 26-57
(10), (4), (3), (2), (2), (2), (1), (1), (1), (1), (1)
Reactivity
Human
(42), (22), (15), (13), (12), (2)
Host
Rabbit
(32), (8), (2), (2), (1)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(35), (18), (10), (7), (4), (4), (2), (1)
Pubmed 3 references available
Catalog no. ABIN389151
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Immunogen This EOMES (TBR2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 26-57 AA from the N-terminal region of human EOMES (TBR2).
Clone RB10349
Isotype Ig
Specificity This EOMES (TBR2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 34~64 amino acids from the N-terminal region of human EOMES.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name EOMES (TBR2)
Background This protein is a member of a conserved protein family that shares a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. A similiar protein disrupted in mice is shown to be essential during trophoblast development and gastrulation.
Synonyms: Eomesodermin homolog, EOMES, TBR2
Molecular Weight 72613 DA
Gene ID 8320
UniProt O95936
Research Area Stem Cells
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.43 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-Eomesodermin (EOMES) (N-Term), (AA 26-57) antibody Western blot analysis of EOMES (arrow) using rabbit polyclonal EOMES Antibody (Human N-term) (ABIN389151). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the EOMES gene (Lane 2) (Origene Technologies).
Background publications Kimura, Nakashima, Ueno et al.: "A novel mammalian T-box-containing gene, Tbr2, expressed in mouse developing brain." in: Brain research. Developmental brain research, Vol. 115, Issue 2, pp. 183-93, 1999 (PubMed).

Intlekofer, Takemoto, Wherry et al.: "Effector and memory CD8+ T cell fate coupled by T-bet and eomesodermin." in: Nature immunology, Vol. 6, Issue 12, pp. 1236-44, 2005 (PubMed).

Baala, Briault, Etchevers et al.: "Homozygous silencing of T-box transcription factor EOMES leads to microcephaly with polymicrogyria and corpus callosum agenesis." in: Nature genetics, Vol. 39, Issue 4, pp. 454-6, 2007 (PubMed).

Hosts (32), (8), (2), (2), (1)
Reactivities (42), (22), (15), (13), (12), (2)
Applications (35), (18), (10), (7), (4), (4), (2), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (10), (4), (3), (2), (2), (2), (1), (1), (1), (1), (1)
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