DTNBP1 antibody (C-Term)

Catalog No. ABIN389170

Product Details anti-DTNBP1 Antibody

Target: DTNBP1 (Dystrobrevin Binding Protein 1 (DTNBP1))

Binding Specificity: AA 296-325, C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DTNBP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This Dtnbp1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 296-325 amino acids from the C-terminal region of human Dtnbp1.

Clone: RB9241

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for DTNBP1

Target: DTNBP1 (Dystrobrevin Binding Protein 1 (DTNBP1))

Alternative Name: Dtnbp1 (DTNBP1 Products)

Background: Dtnp1 may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. A similar protein in mouse is a component of a protein complex termed biogenesis of lysosome-related organelles complex 1 (BLOC-1), and binds to alpha- and beta-dystrobrevins, which are components of the dystrophin-associated protein complex (DPC). Mutations in this protein are associated with Hermansky-Pudlak syndrome type 7. This protein may also be associated with schizophrenia.

Molecular Weight: 39651

Gene ID: 94245

NCBI Accession: NP_080048

UniProt: Q91WZ8

Pathways: Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling