Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogen
This AKR1B1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 102-135 amino acids from the Central region of human AKR1B1.
ADR antibody, ALDR1 antibody, ALR2 antibody, AR antibody, ALDRED antibody, ALR-P-I antibody, Akr1b3 antibody, Akr1b4 antibody, Aldr1 antibody, Alr antibody, RATALDRED antibody, akr1b7 antibody, zgc:86611 antibody, aldo-keto reductase family 1 member B antibody, aldo-keto reductase family 1, member B1 (aldose reductase) antibody, aldo-keto reductase family 1, member B1 (aldose reductase) S homeolog antibody, AKR1B1 antibody, Akr1b1 antibody, akr1b1.S antibody, akr1b1 antibody
Background
AKR1B1 is a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This protein catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol.