Exosome Component 8 (EXOSC8) (AA 243-276), (C-Term) antibody

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Antigen
Synonyms wu:fb79a10, zgc:110381, MGC52847, MGC132146, EXOSC8, MGC79733, CIP3, EAP2, OIP2, RP11-421P11.3, RRP43, Rrp43p, bA421P11.3, p9, 2310032N20Rik, mKIAA4013
Epitope
AA 243-276, C-Term
(5), (2), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(26), (6), (6)
Host
Rabbit
(15), (11)
Clonality (Clone)
Polyclonal ()
Application
Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(21), (10), (10), (8), (3), (3), (3), (2), (1)
Pubmed 1 reference available
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Quantity 400 μL
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Immunogen This EXOSC8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 243-276 AA from the C-terminal region of human EXOSC8.
Clone RB17686
Isotype Ig
Specificity This EXOSC8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 247~276 amino acids from the C-terminal region of human EXOSC8.
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name EXOSC8 (EXOSC8 Antibody Abstract)
Background EXOSC8 is a component of the exosome 3'->5' exoribonuclease complex, a complex that degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3'-untranslated regions. It is required for the 3'-processing of the 7S pre-RNA to the mature 5.8S rRNA and has a 3'-5' exonuclease activity.
Synonyms: Exosome complex exonuclease RRP43, Ribosomal RNA-processing protein 43, Exosome component 8, p9, Opa-interacting protein 2, EXOSC8, OIP2, RRP43
Molecular Weight 29909 DA
Gene ID 11340
UniProt Q96B26
Research Area Translation Factors, Stem Cells, Signaling
Application Notes WB = 1:1000, IHC (p) = 1:50-100, FACS = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-Exosome Component 8 (EXOSC8) (AA 243-276), (C-Term) antibody (ABIN389276) Western blot analysis of anti-EXOSC8 Antibody (C-term) (ABIN389276) in HL60 cell line...
Immunohistochemistry (IHC) image for anti-Exosome Component 8 (EXOSC8) (AA 243-276), (C-Term) antibody (ABIN389276) Formalin-fixed and paraffin-embedded human brain tissue with EXOSC8 Antibody (C-term)...
Flow Cytometry (FACS) image for anti-Exosome Component 8 (EXOSC8) (AA 243-276), (C-Term) antibody (ABIN389276) EXOSC8 Antibody (C-term) (ABIN389276) flow cytometry analysis of HL-60 cells (bottom ...
Background publications Jiang, Altman: "A protein subunit of human RNase P, Rpp14, and its interacting partner, OIP2, have 3'-->5' exoribonuclease activity." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 8, pp. 5295-300, 2002 (PubMed).

Catalog No. ABIN389276
$324.50
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