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MTHFD1 antibody (AA 535-562)
MTHFD1
Reactivity: Human
WB, IF, IHC (p)
Host: Rabbit
Polyclonal
RB19391
unconjugated
Product Details anti-MTHFD1 Antibody
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Target
See all MTHFD1 Antibodies
MTHFD1
(Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 1, Methenyltetrahydrofolate Cyclohydrolase, Formyltetrahydrofolate Synthetase (MTHFD1))
Binding Specificity
All epitopes for MTHFD1 antibodies
AA 535-562
Reactivity
All reactivities for MTHFD1 antibodies
Human
Host
All hosts for MTHFD1 antibodies
Rabbit
Clonality
All clonalities for MTHFD1 antibodies
Polyclonal
Conjugate
All conjugates for MTHFD1 antibodies
This MTHFD1 antibody is un-conjugated
Application
All applications for MTHFD1 antibodies
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Predicted Reactivity
M, Rat
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogen
This MTHFD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 535-562 amino acids from the Central region of human MTHFD1.
Clone
RB19391
Isotype
Ig Fraction
Top Product
Discover our top product MTHFD1 Primary Antibody
Alternatives
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anti-Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 1, Methenyltetrahydrofolate Cyclohydrolase, Formyltetrahydrofolate Synthetase (MTHFD1) (AA 863-912) antibody
MTHFD1
Reactivity: Human, Mouse, Rat, Rabbit, Horse, Zebrafish (Danio rerio), Pig, Dog, Guinea Pig, Monkey, Bat
WB, IHC, IHC (p)
Host: Rabbit
Polyclonal
unconjugated
anti-Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 1, Methenyltetrahydrofolate Cyclohydrolase, Formyltetrahydrofolate Synthetase (MTHFD1) (AA 74-123) antibody
MTHFD1
Reactivity: Human, Mouse, Rat, Rabbit, Zebrafish (Danio rerio), Pig, Monkey
WB, IHC, IHC (p)
Host: Rabbit
Polyclonal
unconjugated
anti-Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 1, Methenyltetrahydrofolate Cyclohydrolase, Formyltetrahydrofolate Synthetase (MTHFD1) (N-Term) antibody
MTHFD1
Reactivity: Human, Mouse, Rat, Rabbit, Horse, Zebrafish (Danio rerio), Dog, Guinea Pig, Cow
WB, IHC
Host: Rabbit
Polyclonal
unconjugated
anti-Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 1, Methenyltetrahydrofolate Cyclohydrolase, Formyltetrahydrofolate Synthetase (MTHFD1) (Middle Region) antibody
MTHFD1
Reactivity: Human, Mouse, Rat, Rabbit, Horse, Zebrafish (Danio rerio), Pig, Dog, Guinea Pig, Cow, Saccharomyces cerevisiae
WB, IHC
Host: Rabbit
Polyclonal
unconjugated
Application Details
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Application Notes
IF: 1:10~50. WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date
6 months
Target Details for MTHFD1
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Target
MTHFD1
(Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 1, Methenyltetrahydrofolate Cyclohydrolase, Formyltetrahydrofolate Synthetase (MTHFD1))
Alternative Name
MTHFD1 (MTHFD1 Products )
Background
MTHFD1 is a protein that possesses three distinct enzymatic activities, 5,10-methylenetetrahydrofolate dehydrogenase, 5,10-methenyltetrahydrofolate cyclohydrolase and 10-formyltetrahydrofolate synthetase. Each of these activities catalyzes one of three sequential reactions in the interconversion of 1-carbon derivatives of tetrahydrofolate, which are substrates for methionine, thymidylate, and de novo purine syntheses. The trifunctional enzymatic activities are conferred by two major domains, an aminoterminal portion containing the dehydrogenase and cyclohydrolase activities and a larger synthetase domain.
Molecular Weight
101559
Gene ID
4522
NCBI Accession
NP_005947
UniProt
P11586
Pathways
Methionine Biosynthetic Process
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