Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogen
This POLR1C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 319-346 amino acids from the C-terminal region of human POLR1C.
zgc:65973 antibody, rpa39 antibody, rpa40 antibody, rpa5 antibody, rpac1 antibody, POLR1C antibody, 40kDa antibody, AA409007 antibody, AA959927 antibody, AL024089 antibody, Polr1e antibody, RPA40 antibody, Rpo1-1 antibody, Ac2-127 antibody, RPA39 antibody, RPA5 antibody, RPAC1 antibody, TCS3 antibody, polymerase (RNA) I polypeptide C antibody, RNA polymerase I subunit C antibody, polymerase (RNA) I polypeptide C L homeolog antibody, polymerase (RNA) I polypeptide C, 30kDa antibody, polr1c antibody, POLR1C antibody, polr1c.L antibody, Polr1c antibody
Background
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I and III which synthesize ribosomal RNA precursors and small RNAs, such as 5S rRNA and tRNAs, respectively. RPAC1 is part of the Pol core element with the central large cleft and probably a clamp element that moves to open and close the cleft.