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Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK) (N-Term), (AA 1-30) antibody

Details for Product No. ABIN389377
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Antigen
Synonyms hnrpk, MGC75642, HNRPK, HNRNPK, CSBP, TUNP, Csbp, Hnrpk, wu:fb37h02, wu:fi34c04, zgc:66162, KBBP, NOVA
Epitope
N-Term, AA 1-30
(6), (6), (6), (4), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(73), (45), (43), (19), (18), (14), (12), (6), (6), (4), (4), (3), (2)
Host
Rabbit
(61), (17)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(66), (27), (22), (17), (16), (11), (10), (7), (2), (2), (2), (1)
Pubmed 1 reference available
Quantity 400 µL
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Catalog No. ABIN389377
291.50 $
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Immunogen This HNRPK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 AA from the N-terminal region of human HNRPK.
Clone RB17648
Isotype Ig
Specificity This HNRPK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1~30 amino acids from the N-terminal region of human HNRPK.
Predicted Reactivity Cow (Bovine),Mouse (Murine),Monkey,Rat (Rattus),Rabbit
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name HNRPK
Background HNRPK belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. HNRPK is located in the nucleoplasm and has three repeats of KH domains that binds to RNAs. The protein is distinct among other hnRNP proteins in its binding preference, it binds tenaciously to poly(C). This protein is also thought to have a role during cell cycle progession.
Synonyms: Heterogeneous nuclear ribonucleoprotein K, Transformation up-regulated nuclear protein, HNRPK
Molecular Weight 42593 DA
Gene ID 3190
UniProt P61978
Research Area Translation Factors, Stem Cells, Signaling
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK) (N-Term), (AA 1-30) antibody Western blot analysis of anti-HNRPK Antibody (N-term) (ABIN389377) in 293 cell line lysates (35 µg/lane). HNRPK(arrow) was detected using the purified polyclonal antibody.
anti-Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK) (N-Term), (AA 1-30) antibody (2) Western blot analysis of anti-HNRPK Antibody (N-term) (ABIN389377) in mouse brain tissue lysates (35 µg/lane). HNRPK(arrow) was detected using the purified polyclonal antibody.
Background publications Hsieh, Matsumoto, Chou et al.: "Hepatitis C virus core protein interacts with heterogeneous nuclear ribonucleoprotein K." in: The Journal of biological chemistry, Vol. 273, Issue 28, pp. 17651-9, 1998 (PubMed).

Validation Images
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