|+1 404 474 4654|
|+1 888 205 9894 (TF)|
Chaperonin Containing TCP1, Subunit 2 (Beta) (CCT2) (C-Term) antibody
|Synonyms||CCTB, 99D8.1, PRO1633, CCT-beta, MGC142074, MGC142076, TCP-1-beta, fa26a01, fc58a11, CHUNP6883, wu:fa26a01, wu:fc58a11, cct2, MGC89448, CCT2, MGC128852, Cctb, MGC94480|
Alternatives Western Blotting (WB), ELISA
|2 references available|
|Quantity||400 µL (0.25 mg/ml)|
|Price||280.50 $ Plus shipping costs $45.00|
|Availability||Will be delivered in 2 to 3 Business Days|
|Immunogen||This CCT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 506~535 amino acids from the C-terminal region of human CCT2.|
|Description||Other names: T-complex protein 1 subunit beta, TCP-1-beta, CCT-beta, CCTB, 99D8.1, CCT2|
|Characteristics||Purified Rabbit Polyclonal Antibody (Pab)|
|Specificity||This CCT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 506~535 amino acids from the C-terminal region of human CCT2.|
|Molecular Weight||57488 DA|
Background: CCT2 is a molecular chaperone that is member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin.
|Application Notes||The suggested dilution is: ELISA ~~ 1:1,000 Western blotting~~ 1:50~100 Flow cytometry ~~ 1:10~50|
|Buffer||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles|
|Research Area||Stem Cells, Protein Modifications|
|Restrictions||For Research Use only|
Zebol, Hewitt, Moretti et al.: "The CCT/TRiC chaperonin is required for maturation of sphingosine kinase 1." in: The international journal of biochemistry & cell biology, Vol. 41, Issue 4, pp. 822-7, 2009 (PubMed).
Abe, Yoon, Kubota et al.: "p90 ribosomal S6 kinase and p70 ribosomal S6 kinase link phosphorylation of the eukaryotic chaperonin containing TCP-1 to growth factor, insulin, and nutrient signaling." in: The Journal of biological chemistry, Vol. 284, Issue 22, pp. 14939-48, 2009 (PubMed).