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Cofilin 1 (Non-Muscle) (CFL1) (AA 4-32), (N-Term) antibody

Details for Product No. ABIN389443, Supplier: Log in to see
Antigen
  • cfl1
  • xac1
  • xac2
  • cfl
  • cb86
  • sb:cb86
  • zgc:56501
  • wu:fb18a04
  • wu:fk77b03
  • 12/8
  • ADF
  • ADF/cofilin
  • Adf
  • CG4254
  • Cadf
  • D-cof
  • D61
  • Dmel\\CG4254
  • T8
  • Tsr
  • cofilin
  • cofilin/ADF
  • cofilin/actin depolymerizing factor homolog
  • l(2)03101
  • l(2)k03101
  • l(2)k05633
  • l(2)k13409
  • ntf
  • CFL
  • AA959946
  • Cof
  • CFL1
  • cofilin 1 (non-muscle)
  • twinstar
  • Cof1p
  • cofilin
  • cofilin 1 (non-muscle)-like
  • cofilin 1, non-muscle
  • COFILIN protein
  • Contrafreeloading
  • cfl1-a
  • cfl1
  • CFL1
  • tsr
  • COF1
  • TSTA_042790
  • Cfl1
  • LOC100341589
  • COFILIN
  • CFL
Epitope
AA 4-32, N-Term
57
32
27
23
15
14
13
13
11
10
7
5
5
4
3
3
3
3
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine)
316
202
165
12
11
9
7
5
2
2
1
1
1
1
Host
Rabbit
250
62
4
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
12
11
11
8
7
7
4
4
3
3
3
3
3
3
3
3
3
1
1
1
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
227
135
106
65
59
41
36
25
18
5
5
4
2
2
1
Options
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Immunogen This CFL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 4-32 AA from the N-terminal region of human CFL1.
Clone RB20525
Isotype Ig
Specificity This CFL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 11~40 amino acids from the N-terminal region of human CFL1.
Predicted Reactivity Cow (Bovine),Pig (Porcine),Monkey,Rat (Rattus)
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name CFL1 (CFL1 Antibody Abstract)
Background Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner.
Synonyms: Cofilin-1, Cofilin, non-muscle isoform, 18 kDa phosphoprotein, p18, CFL, CFL1
Molecular Weight 18502 DA
Gene ID 1072
UniProt P23528
Research Area Stem Cells, Cell Structure
Application Notes WB = 1:1000, IHC (p) = 1:50-100, FACS = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-Cofilin 1 (Non-Muscle) (CFL1) (AA 4-32), (N-Term) antibody (ABIN389443) Western blot analysis of CFL1 Antibody (N-term) (ABIN389443) in MCF-7,Hela cell line ...
Immunohistochemistry (IHC) image for anti-Cofilin 1 (Non-Muscle) (CFL1) (AA 4-32), (N-Term) antibody (ABIN389443) Formalin-fixed and paraffin-embedded human lung carcinoma reacted with CFL1 Antibody ...
Flow Cytometry (FACS) image for anti-Cofilin 1 (Non-Muscle) (CFL1) (AA 4-32), (N-Term) antibody (ABIN389443) Flow cytometric analysis of hela cells using CFL1 Antibody (N-term)(bottom histogram)...
Background publications Fazal, Bijli, Minhajuddin, Rein, Finkelstein, Rahman: "Essential role of cofilin-1 in regulating thrombin-induced RelA/p65 nuclear translocation and intercellular adhesion molecule 1 (ICAM-1) expression in endothelial cells." in: The Journal of biological chemistry, Vol. 284, Issue 31, pp. 21047-56, 2009 (PubMed).