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Details for Product No. ABIN389443

Cofilin 1 (Non-Muscle) (CFL1) (N-Term), (AA 4-32) antibody

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Antigen
Synonyms
CFL, CFL1, AA959946, Cof, cfl1, xac1, xac2, cfl, cb86, sb:cb86, zgc:56501, wu:fb18a04, wu:fk77b03, 12/8, ADF, ADF/cofilin, Adf, CG4254, Cadf, D-cof, D61, Dmel\\CG4254, T8, Tsr, cofilin, cofilin/ADF, c ... show more
Epitope
»Alternatives N-Term, AA 4-32
Reactivity
»Alternatives Human, Mouse (Murine)
Host
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)
Pubmed 1 reference available
Catalog no. ABIN389443
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen This CFL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 4-32 AA from the N-terminal region of human CFL1.
Clone RB20525
Isotype Ig
Specificity This CFL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 11~40 amino acids from the N-terminal region of human CFL1.
Predicted Reactivity Cow (Bovine),Pig (Porcine),Monkey,Rat (Rattus)
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name CFL1
Background Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner.
Synonyms: Cofilin-1, Cofilin, non-muscle isoform, 18 kDa phosphoprotein, p18, CFL, CFL1
Molecular Weight 18502 DA
Gene ID 1072
UniProt P23528
Research Area Stem Cells, Cell Structure
Application Notes Recommend dilutions: WB : 1:1000,IHC : 1:50-100,FC : 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Background publications Fazal, Bijli, Minhajuddin et al.: "Essential role of cofilin-1 in regulating thrombin-induced RelA/p65 nuclear translocation and intercellular adhesion molecule 1 (ICAM-1) expression in endothelial cells." in: The Journal of biological chemistry, Vol. 284, Issue 31, pp. 21047-56, 2009 (PubMed).

Alternatives for antigen "Cofilin 1 (Non-Muscle) (CFL1)", type "Antibodies"
Hosts (107), (25), (4)
Reactivities (135), (82), (72), (24), (24), (13), (13), (12), (4)
Applications (93), (42), (42), (39), (24), (20), (7), (5), (3), (3), (3), (2), (2)
Conjugates (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Epitopes (22), (20), (13), (10), (10), (7), (6), (5), (4), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
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