Cofilin 1 (Non-Muscle) (CFL1) (N-Term), (AA 4-32) antibody

Details for Product No. ABIN389443
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Antigen
Synonyms
CFL, CFL1, AA959946, Cof, cfl1, xac1, xac2, cfl, cb86, sb:cb86, zgc:56501, wu:fb18a04, wu:fk77b03, 12/8, ADF, ADF/cofilin, Adf, CG4254, Cadf, D-cof, D61, Dmel\\CG4254, T8, Tsr, cofilin, cofilin/ADF, c ... show more
CFL, CFL1, AA959946, Cof, cfl1, xac1, xac2, cfl, cb86, sb:cb86, zgc:56501, wu:fb18a04, wu:fk77b03, 12/8, ADF, ADF/cofilin, Adf, CG4254, Cadf, D-cof, D61, Dmel\\CG4254, T8, Tsr, cofilin, cofilin/ADF, cofilin/actin depolymerizing factor homolog, l(2)03101, l(2)k03101, l(2)k05633, l(2)k13409, ntf show less
Epitope
N-Term, AA 4-32
(45), (21), (13), (12), (12), (8), (7), (4), (4), (4), (4), (4), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human, Mouse (Murine)
(209), (142), (138), (60), (52), (36), (28), (25), (12), (4)
Host
Rabbit
(182), (31), (3)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5)
Application
Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)
(143), (78), (50), (50), (48), (25), (12), (5), (3), (3), (2), (1)
Pubmed 1 reference available
Catalog no. ABIN389443
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen This CFL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 4-32 AA from the N-terminal region of human CFL1.
Clone RB20525
Isotype Ig
Specificity This CFL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 11~40 amino acids from the N-terminal region of human CFL1.
Predicted Reactivity Cow (Bovine),Pig (Porcine),Monkey,Rat (Rattus)
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name CFL1
Background Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner.
Synonyms: Cofilin-1, Cofilin, non-muscle isoform, 18 kDa phosphoprotein, p18, CFL, CFL1
Molecular Weight 18502 DA
Gene ID 1072
UniProt P23528
Research Area Stem Cells, Cell Structure
Application Notes WB = 1:1000, IHC = 1:50-100, FACS = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-Cofilin 1 (Non-Muscle) (CFL1) (N-Term), (AA 4-32) antibody Western blot analysis of CFL1 Antibody (N-term) (ABIN389443) in MCF-7,Hela cell line and mouse brain tissue lysates (35 µg/lane). CFL1 (arrow) was detected using the purified polyclonal antibody.(2 µg/mL)
anti-Cofilin 1 (Non-Muscle) (CFL1) (N-Term), (AA 4-32) antibody (2) Formalin-fixed and paraffin-embedded human lung carcinoma reacted with CFL1 Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.
anti-Cofilin 1 (Non-Muscle) (CFL1) (N-Term), (AA 4-32) antibody (3) Flow cytometric analysis of hela cells using CFL1 Antibody (N-term)(bottom histogram) compared to a negative control cell (top histogram)FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Background publications Fazal, Bijli, Minhajuddin et al.: "Essential role of cofilin-1 in regulating thrombin-induced RelA/p65 nuclear translocation and intercellular adhesion molecule 1 (ICAM-1) expression in endothelial cells." in: The Journal of biological chemistry, Vol. 284, Issue 31, pp. 21047-56, 2009 (PubMed).

Hosts (182), (31), (3)
Reactivities (209), (142), (138), (60), (52), (36), (28), (25), (12), (4)
Applications (143), (78), (50), (50), (48), (25), (12), (5), (3), (3), (2), (1)
Conjugates (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5)
Epitopes (45), (21), (13), (12), (12), (8), (7), (4), (4), (4), (4), (4), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Validation Images
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