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Cyclin-Dependent Kinase 1 (CDK1) (pThr161) antibody

Details for Product No. ABIN389536
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Antigen
Synonyms
CDC2, CDC28A, P34CDC2, Cdc2, Cdc2a, p34, cdc2, wu:fc30e01, zgc:92032, 5363, CDCDm, CDK1, CDK1/CDC2, CG5363, Cdk-1, Cdk1, Dcdc2, Dm cdc2, DmCdc2, DmCdk1, Dmcdc2, Dmel\\CG5363, cdc, cdc2Dm, cdk1,  ... show more
CDC2, CDC28A, P34CDC2, Cdc2, Cdc2a, p34, cdc2, wu:fc30e01, zgc:92032, 5363, CDCDm, CDK1, CDK1/CDC2, CG5363, Cdk-1, Cdk1, Dcdc2, Dm cdc2, DmCdc2, DmCdk1, Dmcdc2, Dmel\\CG5363, cdc, cdc2Dm, cdk1, dCdk1, group 4, l(2)31Eh, CDC2A, CDC2AAT, CDK2, CDKA1, CDKA;1, CYCLIN-DEPENDENT KINASE A;1, cell division control 2 show less
Epitope
pThr161
(57), (53), (51), (28), (18), (17), (17), (13), (12), (9), (7), (6), (6), (6), (6), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(481), (249), (237), (43), (38), (27), (26), (26), (15), (7), (6), (4), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Host
Rabbit
(397), (128)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(21), (15), (15), (9), (9), (9), (6), (6), (6), (6), (6), (6), (6), (6), (1), (1)
Application
Western Blotting (WB), Immunohistochemistry (IHC)
(436), (213), (122), (105), (65), (63), (60), (44), (22), (17), (11), (9), (3), (1), (1), (1), (1), (1), (1)
Pubmed 3 references available
Quantity 400 µL
Options
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Catalog No. ABIN389536
291.50 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen This CDC2 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T161 of human CDC2.
Clone RB05681
Isotype Ig
Specificity This Phospho-CDC2-T161 antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T161 of human CDC2.
Predicted Reactivity Cow (Bovine),Caenorhabditis elegans (C. elegans),Mouse (Murine),Rat (Rattus)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name CDC2
Background CDC2 (CDK3) complements cdc28 mutants of Saccharomyces cerevisiae suggesting that it may be involved in cell cycle control. CDK3 can phosphorylate histone H1 and interacts with an unknown type of cyclin.
Synonyms: Cell division protein kinase 3, CDK3,
Molecular Weight 35046 DA
Gene ID 983
UniProt P06493
Research Area Apoptosis/Necrosis, Phospho-specific antibodies, Cell Signaling, Protein Modifications, Cell Cycle, Signaling, Chromatin, Cell Structure
Application Notes WB = 1:1000, IHC = 1:50-100
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-Cyclin-Dependent Kinase 1 (CDK1) (pThr161) antibody Western blot analysis of anti-Phospho-CDC2 Pab(ABIN389536) in mouse brain tissue lysate (35 µg/lane). Phospho-CDC2(arrow) was detected using the purified polyclonal antibody (1:60 dilution).
anti-Cyclin-Dependent Kinase 1 (CDK1) (pThr161) antibody (2) Western blot analysis of anti-Phospho-CDC2-T161 Pab (ABIN389536) transiently transfected HEK-293 cell line lysate (1 µg/lane). Phospho-CDC2 pab(arrow) was detected using the purified polyclonal antibody (1:1500 dilution).
anti-Cyclin-Dependent Kinase 1 (CDK1) (pThr161) antibody (3) Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma
Background publications Meyerson, Enders, Wu et al.: "A family of human cdc2-related protein kinases." in: The EMBO journal, Vol. 11, Issue 8, pp. 2909-17, 1992 (PubMed).

Bullrich, MacLachlan, Sang et al.: "Chromosomal mapping of members of the cdc2 family of protein kinases, cdk3, cdk6, PISSLRE, and PITALRE, and a cdk inhibitor, p27Kip1, to regions involved in human cancer." in: Cancer research, Vol. 55, Issue 6, pp. 1199-205, 1995 (PubMed).

Ren, Rollins: "Cyclin C/cdk3 promotes Rb-dependent G0 exit." in: Cell, Vol. 117, Issue 2, pp. 239-51, 2004 (PubMed).

Hosts (397), (128)
Reactivities (481), (249), (237), (43), (38), (27), (26), (26), (15), (7), (6), (4), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applications (436), (213), (122), (105), (65), (63), (60), (44), (22), (17), (11), (9), (3), (1), (1), (1), (1), (1), (1)
Conjugates (21), (15), (15), (9), (9), (9), (6), (6), (6), (6), (6), (6), (6), (6), (1), (1)
Epitopes (57), (53), (51), (28), (18), (17), (17), (13), (12), (9), (7), (6), (6), (6), (6), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN389536
291.50 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Validation Images
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