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Details for Product No. ABIN389536

Cyclin-Dependent Kinase 1 (CDK1) (pThr161) antibody

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Antigen
Synonyms
CDC2, CDC28A, P34CDC2, Cdc2, Cdc2a, p34, cdc2, wu:fc30e01, zgc:92032, 5363, CDCDm, CDK1, CDK1/CDC2, CG5363, Cdk-1, Cdk1, Dcdc2, Dm cdc2, DmCdc2, DmCdk1, Dmcdc2, Dmel\\CG5363, cdc, cdc2Dm, cdk1,  ... show more
Epitope
»Alternatives pThr161
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB), Immunohistochemistry (IHC)
Pubmed 3 references available
Catalog no. ABIN389536
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Immunogen This CDC2 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T161 of human CDC2.
Clone RB05681
Isotype Ig
Specificity This Phospho-CDC2-T161 antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T161 of human CDC2.
Predicted Reactivity Cow (Bovine),Caenorhabditis elegans (C. elegans),Mouse (Murine),Rat (Rattus)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name CDC2
Background CDC2 (CDK3) complements cdc28 mutants of Saccharomyces cerevisiae suggesting that it may be involved in cell cycle control. CDK3 can phosphorylate histone H1 and interacts with an unknown type of cyclin.
Synonyms: Cell division protein kinase 3, CDK3,
Molecular Weight 35046 DA
Gene ID 983
UniProt P06493
Research Area Apoptosis/Necrosis, Phospho-specific antibodies, Cell Signaling, Protein Modifications, Cell Cycle, Signaling, Chromatin, Cell Structure
Application Notes Recommend dilutions: WB : 1:1000,IHC : 1:50-100
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Background publications Meyerson, Enders, Wu et al.: "A family of human cdc2-related protein kinases." in: The EMBO journal, Vol. 11, Issue 8, pp. 2909-17, 1992 (PubMed).

Bullrich, MacLachlan, Sang et al.: "Chromosomal mapping of members of the cdc2 family of protein kinases, cdk3, cdk6, PISSLRE, and PITALRE, and a cdk inhibitor, p27Kip1, to regions involved in human cancer." in: Cancer research, Vol. 55, Issue 6, pp. 1199-205, 1995 (PubMed).

Ren, Rollins: "Cyclin C/cdk3 promotes Rb-dependent G0 exit." in: Cell, Vol. 117, Issue 2, pp. 239-51, 2004 (PubMed).

Alternatives for antigen "Cyclin-Dependent Kinase 1 (CDK1)", type "Antibodies"
Hosts (337), (129)
Reactivities (420), (248), (236), (45), (38), (31), (27), (26), (14), (9), (7), (4), (4), (3), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applications (376), (158), (129), (83), (73), (60), (53), (33), (15), (11), (11), (11), (7), (4), (3), (3), (1), (1), (1), (1)
Conjugates (13), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (1), (1)
Epitopes (50), (48), (45), (24), (17), (15), (10), (4), (4), (4), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
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