You are viewing an incomplete version of our website. Please click to reload the website as full version.

MAPK14 antibody (Mitogen-Activated Protein Kinase 14) (pTyr322)

Details for Product anti-MAPK14 Antibody No. ABIN389823, Supplier: Login to see New
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

(27), (23), (17), (13), (13), (11), (11), (9), (8), (7), (7), (7), (5), (5), (5), (4), (4), (4), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
(191), (85), (76), (19), (9), (8), (7), (4), (3), (3), (3), (3), (3), (3), (1), (1)
(164), (31), (2), (2)
Clonality (Clone)
Polyclonal ()
This MAPK14 antibody is un-conjugated
(7), (7), (6), (5), (5), (5)
Dot Blot (DB)
(175), (78), (55), (28), (26), (13), (11), (9), (8), (7), (7), (2), (1)
Pubmed 2 references available
Supplier Login to see New
Catalog number from supplier Login to see New
Quantity 400 μL
Shipping to United States ( )
Immunogen This MAPK14 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y323 of human MAPK14.
Clone RB13246
Isotype Ig
Specificity This Phospho-MAPK14-pY323 antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y323 of human MAPK14.
Predicted Reactivity Mouse (Murine)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name MAPK14 (MAPK14 Antibody Abstract)
Background MAPK14 is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response.
Synonyms: Mitogen-activated protein kinase 14, Mitogen-activated protein kinase p38alpha, MAP kinase p38alpha, Cytokine suppressive anti-inflammatory drug binding protein, CSAID binding protein, CSBP, MAX-interacting protein 2, MAP kinase MXI2, SAPK2A
Molecular Weight 41293 DA
Gene ID 1432
UniProt Q16539
Research Area Cell Cycle, Phospho-specific antibodies, Transcription Factors, Signaling, Cell Structure
Pathways MAPK Signaling, TCR Signaling, Neurotrophin Signaling Pathway
Application Notes DB = 1:500
Restrictions For Research Use only
Format Liquid
Concentration 0.29 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Dot Blot (DB) image for anti-MAPK14 antibody (Mitogen-Activated Protein Kinase 14) (pTyr322) (ABIN389823) Dot blot analysis of anti-MAPK14-pY322 Phospho-specific Pab (ABIN389823) on nitrocell...
Background publications Cheung, Campbell, Nebreda et al.: "Feedback control of the protein kinase TAK1 by SAPK2a/p38alpha." in: The EMBO journal, Vol. 22, Issue 21, pp. 5793-805, 2003 (PubMed).

Dean, Sarsfield, Tsounakou et al.: "p38 Mitogen-activated protein kinase stabilizes mRNAs that contain cyclooxygenase-2 and tumor necrosis factor AU-rich elements by inhibiting deadenylation." in: The Journal of biological chemistry, Vol. 278, Issue 41, pp. 39470-6, 2003 (PubMed).

Catalog No. ABIN389823

Order hotline:

  • +1 877 302 8632
  • +1 888 205 9894 (TF)