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DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) (pSer154) antibody

Details for Product No. ABIN389917, Supplier: Log in to see
Antigen
  • cb1075
  • cb983
  • dmnt1
  • fb05h01
  • mta
  • wu:fb05h01
  • ADCADN
  • AIM
  • CXXC9
  • DNMT
  • HSN1E
  • MCMT
  • DDM2
  • DECREASED DNA METHYLATION 2
  • DMT01
  • DMT1
  • DNA METHYLTRANSFERASE
  • DNA METHYLTRANSFERASE 01
  • DNA METHYLTRANSFERASE 1
  • MET2
  • METHYLTRANSFERASE 2
  • METHYLTRANSFERASE I
  • METI
  • methyltransferase 1
  • Cxxc9
  • Dnmt
  • Dnmt1o
  • MTase
  • Met-1
  • Met1
  • MommeD2
  • m.MmuI
  • DNA (cytosine-5-)-methyltransferase 1
  • DNA (cytosine-5)-methyltransferase 1
  • DNA methyltransferase (cytosine-5) 1
  • DNMT1
  • dnmt1
  • Dnmt1
  • MET1
Epitope
pSer154
66
43
36
21
21
20
19
16
15
15
15
11
9
7
7
7
6
6
5
4
4
3
3
2
2
2
2
2
2
2
1
1
1
1
1
1
1
Reactivity
Human
430
183
95
73
40
26
8
8
6
5
5
3
2
2
2
1
1
1
1
Host
Rabbit
267
137
20
8
3
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
24
24
21
19
18
18
6
5
5
5
5
5
5
5
5
5
5
5
4
4
4
4
4
4
4
4
4
3
2
1
1
1
1
1
1
1
1
1
1
Application
Dot Blot (DB)
285
139
119
113
89
72
53
53
51
38
37
16
6
5
3
2
2
2
2
1
Options
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Immunogen This Dnmt1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S154 of human Dnmt1.
Clone RB18429
Isotype Ig
Specificity This Phospho-Dnmt1-pS154 antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S154 of human Dnmt1.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name Dnmt1 (DNMT1 Antibody Abstract)
Background DNA (cytosine-5-)-methyltransferase 1 has a role in the establishment and regulation of tissue-specific patterns of methylated cytosine residues. Aberrant methylation patterns are associated with certain human tumors and developmental abnormalities.
Synonyms: DNA (cytosine-5)-methyltransferase 1, Dnmt1, DNA methyltransferase HsaI, DNA MTase HsaI, MCMT, M.HsaI, AIM, DNMT
Molecular Weight 183165 DA
Gene ID 1786
UniProt P26358
Research Area Signaling, Protein Modifications, Phospho-specific antibodies
Application Notes DB = 1:500
Restrictions For Research Use only
Format Liquid
Concentration 0.32 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Dot Blot (DB) image for anti-DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) (pSer154) antibody (ABIN389917) Dot blot analysis of anti-Phospho-Dnmt1-pS154 Antibody (ABIN389917) on nitrocellulose...
Background publications Liao, Siu, Chan, Wong, Ngan, Chan, Li, Khoo, Cheung: "Hypermethylation of RAS effector related genes and DNA methyltransferase 1 expression in endometrial carcinogenesis." in: International journal of cancer. Journal international du cancer, Vol. 123, Issue 2, pp. 296-302, 2008 (PubMed).

Dion, Lin, Hubert, Waterland, Wilson: "Dnmt1 deficiency promotes CAG repeat expansion in the mouse germline." in: Human molecular genetics, Vol. 17, Issue 9, pp. 1306-17, 2008 (PubMed).