Phosphinothricin N-Acetyltransferase (BAR2) (pSer261) antibody

Details for Product No. ABIN389931
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Antigen
Epitope
pSer261
(1), (1), (1), (1), (1)
Reactivity
Human
(3), (1)
Host
Rabbit
(3)
Clonality (Clone)
Polyclonal ()
Application
Dot Blot (DB)
(2), (1), (1)
Pubmed 1 reference available
Quantity 400 μL
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Catalog No. ABIN389931
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Immunogen This BAR2 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S261 of human BAR2.
Clone RB15325
Isotype Ig
Specificity This Phospho-BAR2-pS261 antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide between 243~272 amino acids surrounding S261 of human BAR2.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name BAR2
Background Beta-2-adrenergic receptor is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor.
Synonyms: Beta-2 adrenoceptor, Beta-2 adrenoreceptor, ADRB2, ADRB2R, B2AR
Molecular Weight 46426 DA
Gene ID 154
NCBI Accession NP_000015
Research Area Cell Signaling, Phospho-specific antibodies, Cell Structure
Application Notes DB = 1:500
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-Phosphinothricin N-Acetyltransferase (BAR2) (pSer261) antibody Dot blot analysis of anti-Phospho-BAR2-pS261 Antibody (ABIN389931) on nitrocellulose membrane. 50 ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5 µg/mL.
Background publications Cherezov, Rosenbaum, Hanson et al.: "High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor." in: Science (New York, N.Y.), Vol. 318, Issue 5854, pp. 1258-65, 2007 (PubMed).

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