HIPK2 antibody (Homeodomain Interacting Protein Kinase 2) (pTyr361)

Details for Product anti-HIPK2 Antibody No. ABIN389999, Supplier: Log in to see
Antigen
  • HIPK2
  • cb1009
  • si:dkey-16j24.2
  • si:dkey-239k7.1
  • wu:fk56d12
  • pro0593
  • MGC146781
  • PRO0593
  • 1110014O20Rik
  • B230339E18Rik
  • Stank
  • PKM
  • homeodomain interacting protein kinase 2
  • serine/threonine protein kinase
  • HIPK2
  • hipk2
  • Hipk2
Alternatives
anti-Human HIPK2 antibody for Dot Blot
Epitope
pTyr361
17
16
13
11
10
7
4
3
3
2
1
1
1
1
1
1
Reactivity
Human
96
12
8
3
2
2
2
2
2
1
1
1
1
Host
Rabbit
83
13
Clonality (Clone)
Polyclonal ()
Conjugate
This HIPK2 antibody is un-conjugated
8
8
8
8
8
4
Application
Dot Blot (DB)
64
60
36
15
14
4
4
3
3
1
Options
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Immunogen This HIPK2 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y361 of human HIPK2.
Clone RB16666
Isotype Ig
Specificity This Phospho-HIPK2-pY361 antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide between 351~380 amino acids surrounding Y361 of human HIPK2.
Predicted Reactivity Mouse (Murine),Rat (Rattus)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name HIPK2 (HIPK2 Antibody Abstract)
Background HIPK2 is a conserved serine/threonine nuclear kinase that interacts with homeodomain transcription factors.
Synonyms: Homeodomain-interacting protein kinase 2,
Molecular Weight 130966 DA
Gene ID 28996
UniProt Q9H2X6
Research Area Phospho-specific antibodies, Protein Modifications
Pathways Cell Division Cycle
Application Notes DB = 1:500
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Dot Blot (DB) image for anti-HIPK2 antibody (Homeodomain Interacting Protein Kinase 2) (pTyr361) (ABIN389999) Dot blot analysis of anti-Phospho-HIPK2-pY361 Antibody (ABIN389999) on nitrocellulose...
Background publications Guha, Chaerkady, Marimuthu, Patterson, Kashyap, Harsha, Sato, Bader, Lash, Minna, Pandey, Varmus: "Comparisons of tyrosine phosphorylated proteins in cells expressing lung cancer-specific alleles of EGFR and KRAS." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 37, pp. 14112-7, 2008 (PubMed).

Daub, Olsen, Bairlein, Gnad, Oppermann, Körner, Greff, Kéri, Stemmann, Mann: "Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle." in: Molecular cell, Vol. 31, Issue 3, pp. 438-48, 2008 (PubMed).

Guo, Villén, Kornhauser, Lee, Stokes, Rikova, Possemato, Nardone, Innocenti, Wetzel, Wang, MacNeill, Mitchell, Gygi, Rush, Polakiewicz, Comb: "Signaling networks assembled by oncogenic EGFR and c-Met." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 2, pp. 692-7, 2008 (PubMed).

Rikova, Guo, Zeng, Possemato, Yu, Haack, Nardone, Lee, Reeves, Li, Hu, Tan, Stokes, Sullivan, Mitchell, Wetzel, Macneill, Ren, Yuan, Bakalarski, Villen, Kornhauser, Smith, Li, Zhou, Gygi, Gu et al.: "Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer. ..." in: Cell, Vol. 131, Issue 6, pp. 1190-203, 2007 (PubMed).