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TERT antibody (pTyr707)

TERT Reactivity: Human IF, DB Host: Rabbit Polyclonal RB16840 unconjugated
Catalog No. ABIN390002
  • Target See all TERT Antibodies
    TERT (Telomerase Reverse Transcriptase (TERT))
    Binding Specificity
    • 16
    • 16
    • 10
    • 9
    • 7
    • 5
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pTyr707
    Reactivity
    • 105
    • 38
    • 20
    • 5
    • 1
    • 1
    Human
    Host
    • 107
    • 6
    • 1
    Rabbit
    Clonality
    • 98
    • 16
    Polyclonal
    Conjugate
    • 59
    • 8
    • 7
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This TERT antibody is un-conjugated
    Application
    • 75
    • 55
    • 39
    • 27
    • 16
    • 16
    • 15
    • 13
    • 7
    • 7
    • 6
    • 4
    • 3
    • 3
    • 1
    • 1
    Immunofluorescence (IF), Dot Blot (DB)
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This TERT Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y707 of human TERT.
    Clone
    RB16840
    Isotype
    Ig Fraction
    Top Product
    Discover our top product TERT Primary Antibody
  • Application Notes
    IF: 1:10~50. DB: 1:500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Radan, Hughes, Teichroeb, Vieira Zamora, Jewer, Postovit, Betts: "Microenvironmental regulation of telomerase isoforms in human embryonic stem cells." in: Stem cells and development, Vol. 23, Issue 17, pp. 2046-66, (2014) (PubMed).

    Pecec, Voiculetz: "An antibody sandwich method for the radioimmunoassay of human alpha-fetoprotein." in: Immunochemistry, Vol. 11, Issue 12, pp. 771-5, (1975) (PubMed).

  • Target
    TERT (Telomerase Reverse Transcriptase (TERT))
    Alternative Name
    TERT (TERT Products)
    Synonyms
    CMM9 antibody, DKCA2 antibody, DKCB4 antibody, EST2 antibody, PFBMFT1 antibody, TCS1 antibody, TP2 antibody, TRT antibody, hEST2 antibody, hTRT antibody, chTERT antibody, Tert antibody, ATTERT antibody, F5E19.190 antibody, F5E19_190 antibody, telomerase reverse transcriptase antibody, tert antibody, TR antibody, est2 antibody, tcs1 antibody, telomerase antibody, tert-A antibody, tp2 antibody, trt antibody, xTERT antibody, telomerase reverse transcriptase antibody, Telomerase Reverse Transcriptase antibody, Tertp antibody, Telomerase catalytic subunit antibody, telomerase reverse transcriptase L homeolog antibody, TERT antibody, trt-1 antibody, Tert antibody, tert antibody, CMU_003490 antibody, VDBG_04487 antibody, GL50803_16225 antibody, tert.L antibody
    Background
    Telomerase is a ribonucleoprotein polymerase that maintains telomere ends by addition of the telomere repeat TTAGGG. The enzyme consists of a protein component with reverse transcriptase activity, and an RNA component which serves as a template for the telomere repeat. Telomerase expression plays a role in cellular senescence, as it is normally repressed in postnatal somatic cells resulting in progressive shortening of telomeres. Deregulation of telomerase expression in somatic cells may be involved in oncogenesis. Studies in mouse suggest that telomerase also participates in chromosomal repair, since de novo synthesis of telomere repeats may occur at double-stranded breaks.
    Molecular Weight
    126997
    Gene ID
    7015
    NCBI Accession
    NP_001180305, NP_937983
    UniProt
    O14746
    Pathways
    Telomere Maintenance
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