MAGEA9 antibody (AA 171-198)

Catalog No. ABIN390111

Product Details anti-MAGEA9 Antibody

Target: MAGEA9 (Melanoma Antigen Family A, 9 (MAGEA9))

Binding Specificity: AA 171-198

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAGEA9 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This MAGEA9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 171-198 amino acids from the Central region of human MAGEA9.

Clone: RB2099

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-MAGEA9 antibody (ABIN390111)

Zhang, Zhai, Wang, Feng, Zhu, Xu, Mao, Huang: "High expression of MAGE-A9 in tumor and stromal cells of non-small cell lung cancer was correlated with patient poor survival." in: International journal of clinical and experimental pathology, Vol. 8, Issue 1, pp. 541-50, (2015) (PubMed).

Zhan, Zhang, Zhang, Ma, Wu, Gu, Li, Yang: "Prognostic value of MAGE-A9 expression in patients with colorectal cancer." in: Clinics and research in hepatology and gastroenterology, (2015) (PubMed).

Han, Jiang, Wu, Zhang, Lu: "Expression and prognostic value of MAGE-A9 in laryngeal squamous cell carcinoma." in: International journal of clinical and experimental pathology, Vol. 7, Issue 10, pp. 6734-42, (2014) (PubMed).

Target Details for MAGEA9

Target: MAGEA9 (Melanoma Antigen Family A, 9 (MAGEA9))

Alternative Name: MAGEA9 (MAGEA9 Products)

Synonyms: CT1.9 antibody, MAGE9 antibody, MAGEA9B antibody, MAGEA9 antibody, MAGE family member A9 antibody, melanoma antigen family A, 9B antibody, melanoma-associated antigen 9 antibody, MAGEA9 antibody, MAGEA9B antibody, LOC525400 antibody

Background: MAGEA9 is a member of the MAGEA gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50 to 80 % sequence identity between each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are expressed at a high level in a number of tumors of various histologic types, and are silent in normal tissues with the exception of testis and placenta. The MAGEA genes are clustered on chromosome Xq28. They may be implicated in some hereditary disorders, such as dyskeratosis congenita.

Gene ID: 4108

NCBI Accession: NP_001074259, NP_005356

UniProt: P43362