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Matrix Metallopeptidase 15 (Membrane-inserted) (MMP15) (N-Term), (AA 165-194) antibody

Details for Product No. ABIN390139
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Antigen
Synonyms MT2-MMP, AI503551, MTMMP2, SMCP-2
Epitope
N-Term, AA 165-194
(14), (7), (4), (4), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human, Mouse (Murine)
(86), (42), (19), (18), (17), (17), (1)
Host
Rabbit
(90), (5)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(3), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)
(69), (39), (31), (22), (17), (15), (14), (5), (4), (1)
Pubmed 2 references available
Quantity 400 µL
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Catalog No. ABIN390139
291.50 $
Plus shipping costs $45.00
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  • +1 404 474 4654
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Immunogen This MMP15 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 165-194 AA from the N-terminal region of human MMP15.
Clone RB2029
Isotype Ig
Specificity This MMP15 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human MMP15.
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name MMP15
Background Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, MMP15 is a member of the membrane-type MMP (MT-MMP) subfamily, each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted.
Molecular Weight 75807 DA
Gene ID 4324
UniProt NP_002419
Research Area Stem Cells, Cell Structure, Protein Modifications, Cancer
Application Notes WB = 1:1000, IHC = 1:50-100, FACS = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-Matrix Metallopeptidase 15 (Membrane-inserted) (MMP15) (N-Term), (AA 165-194) antibody The anti-MMP15 N-term Antibody (ABIN390139) is used in Western blot to detect MMP15 in mouse brain tissue lysate (lane 1) and HL60 cell lysate (lane 2) lysate.
anti-Matrix Metallopeptidase 15 (Membrane-inserted) (MMP15) (N-Term), (AA 165-194) antibody (2) Formalin-fixed and paraffin-embedded human colon carcinoma with MMP15 Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.
anti-Matrix Metallopeptidase 15 (Membrane-inserted) (MMP15) (N-Term), (AA 165-194) antibody (3) Flow cytometric analysis of WiDr cells using MMP15 Antibody (N-term)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Background publications Mattei, Roeckel, Olsen et al.: "Genes of the membrane-type matrix metalloproteinase (MT-MMP) gene family, MMP14, MMP15, and MMP16, localize to human chromosomes 14, 16, and 8, respectively." in: Genomics, Vol. 40, Issue 1, pp. 168-9, 1997 (PubMed).

Sato, Tanaka, Takino et al.: "Assignment of the human genes for membrane-type-1, -2, and -3 matrix metalloproteinases (MMP14, MMP15, and MMP16) to 14q12.2, 16q12.2-q21, and 8q21, respectively, by in situ hybridization." in: Genomics, Vol. 39, Issue 3, pp. 412-3, 1997 (PubMed).

Hosts (90), (5)
Reactivities (86), (42), (19), (18), (17), (17), (1)
Applications (69), (39), (31), (22), (17), (15), (14), (5), (4), (1)
Conjugates (3), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (14), (7), (4), (4), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN390139
291.50 $
Plus shipping costs $45.00
Add to Basket

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Validation Images
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