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CD14 antibody (CD14 Molecule) (AA 292-322)

Details for Product anti-CD14 Antibody No. ABIN390261, Supplier: Log in to see
Antigen
Alternatives
anti-Human CD14 antibody for Functional Studies
Epitope
AA 292-322, C-Term
27
23
19
15
12
11
11
9
8
6
6
6
5
4
4
3
3
2
2
2
2
2
2
2
1
1
1
1
Reactivity
Human
919
119
108
87
79
78
58
54
54
53
50
45
34
26
24
19
13
12
9
9
8
4
3
2
1
Host
Rabbit
852
103
62
25
3
Clonality (Clone)
Polyclonal ()
Conjugate
This CD14 antibody is un-conjugated
111
105
71
47
27
25
20
20
18
17
13
13
13
13
13
13
9
9
8
8
8
8
7
7
6
6
5
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4
4
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
835
288
252
146
145
105
66
66
52
40
14
13
12
7
4
4
3
3
3
3
3
2
2
1
1
1
1
1
Supplier
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Immunogen This CD14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 292-322 AA from the C-terminal region of human CD14.
Clone RB14107
Isotype Ig
Specificity This CD14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 300~329 amino acids from the C-terminal region of human CD14.
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name CD14 (CD14 Antibody Abstract)
Background CD14 is a surface protein preferentially expressed on monocytes/macrophages. It binds lipopolysaccharide binding protein and recently has been shown to bind apoptotic cells.
Synonyms: Monocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein, Monocyte differentiation antigen CD14, urinary form, Monocyte differentiation antigen CD14, membrane-bound form, CD14
Molecular Weight 40076 DA
Gene ID 929
UniProt P08571
Research Area Apoptosis/Necrosis, Cell Structure
Pathways TLR Signaling
Application Notes WB = 1:1000, IHC (p) = 1:10-50, FACS = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Immunohistochemistry (IHC) image for anti-CD14 antibody (CD14 Molecule) (AA 292-322) (ABIN390261) Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with CD14 an...
Western Blotting (WB) image for anti-CD14 antibody (CD14 Molecule) (AA 292-322) (ABIN390261) Western blot analysis of CD14(arrow) using rabbit polyclonal CD14 Antibody (C-term) (...
Western Blotting (WB) image for anti-CD14 antibody (CD14 Molecule) (AA 292-322) (ABIN390261) CD14 Antibody (C-term) (ABIN390261) western blot analysis in A549 cell line lysates (...
Background publications Donati, Liljenberg, Padyukov, Berglundh: "Local expression of interleukin-10 and mCD14 in relation to the -1087 IL-10 and -159 CD14 gene polymorphisms in chronic periodontitis." in: Journal of periodontology, Vol. 79, Issue 3, pp. 517-24, 2008 (PubMed).

Setoguchi, Nasu, Yoshida, Higuchi, Akizuki, Yamamoto: "Mouse and human CD14 (myeloid cell-specific leucine-rich glycoprotein) primary structure deduced from cDNA clones." in: Biochimica et biophysica acta, Vol. 1008, Issue 2, pp. 213-22, 1989 (PubMed).

Goyert, Ferrero, Rettig, Yenamandra, Obata, Le Beau: "The CD14 monocyte differentiation antigen maps to a region encoding growth factors and receptors." in: Science (New York, N.Y.), Vol. 239, Issue 4839, pp. 497-500, 1988 (PubMed).