RCAN1 antibody (AA 75-104)
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- Target See all RCAN1 Antibodies
- RCAN1 (Regulator of Calcineurin 1 (RCAN1))
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Binding Specificity
- AA 75-104
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This RCAN1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Purification
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- Immunogen
- This DSCR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 75-104 amino acids from the Central region of human DSCR1.
- Clone
- RB2181
- Isotype
- Ig Fraction
- Top Product
- Discover our top product RCAN1 Primary Antibody
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- Application Notes
- WB: 1:1000. WB: 1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- Expiry Date
- 6 months
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- Target
- RCAN1 (Regulator of Calcineurin 1 (RCAN1))
- Alternative Name
- DSCR1 (RCAN1 Products)
- Synonyms
- ADAPT78 antibody, CSP1 antibody, DSC1 antibody, DSCR1 antibody, MCIP1 antibody, RCN1 antibody, RCAN1 antibody, 2410048A02Rik antibody, AA408855 antibody, AI429645 antibody, AL024459 antibody, AV028423 antibody, Adapt78 antibody, CALP1L antibody, Dscr1 antibody, Mcip1 antibody, dscr1 antibody, rcan1 antibody, wu:fr92c05 antibody, adapt78 antibody, csp1 antibody, dsc1 antibody, mcip1 antibody, MGC53636 antibody, rcn1 antibody, MGC69428 antibody, regulator of calcineurin 1 antibody, regulator of calcineurin 1b antibody, regulator of calcineurin 1 L homeolog antibody, Down syndrome critical region gene 1 antibody, RCAN1 antibody, Rcan1 antibody, rcan1b antibody, rcan1.L antibody, dscr1 antibody, rcan1 antibody
- Background
- DSCR1 (calcipressin 1) interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. Thr gene for this protein is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease.
- Molecular Weight
- 28079
- Gene ID
- 1827
- NCBI Accession
- NP_004405, NP_981962, NP_981963
- UniProt
- P53805
- Pathways
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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