Transforming Growth Factor beta Regulator 1 (TBRG1) (N-Term), (AA 6-36) antibody

Details for Product No. ABIN390357
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Antigen
Synonyms MGC89629, AA408552, AA409675, Niam, Tb-5, mFLJ00213, NIAM, TB-5
Epitope
N-Term, AA 6-36
(6), (1), (1)
Reactivity
Human
(24), (14), (14), (12), (12), (12)
Host
Rabbit
(24)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(15), (10), (5), (3), (1)
Pubmed 1 reference available
Quantity 400 μL
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Catalog No. ABIN390357
291.50 $
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Immunogen This TBRG1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 6-36 AA from the N-terminal region of human TBRG1.
Clone RB14593
Isotype Ig
Specificity This TBRG1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 14~43 amino acids from the N-terminal region of human TBRG1.
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name TBRG1
Background TBRG1 acts as a growth inhibitor. It can activate TP53/p53, cause G1 arrest and collaborate with CDKN2A to restrict proliferation, but it does not require either protein to inhibit DNA synthesis. TBRG1 redistributes CDKN2A into the nucleoplasm, and is involved in maintaining chromosomal stability.
Synonyms: Transforming growth factor beta regulator 1, Nuclear interactor of ARF and Mdm2, TBRG1, NIAM
Molecular Weight 44946 DA
Gene ID 84897
UniProt Q3YBR2
Research Area Cell Cycle, Signaling, Chromatin, Cell Structure
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-Transforming Growth Factor beta Regulator 1 (TBRG1) (N-Term), (AA 6-36) antibody Western blot analysis of anti-TBRG1 Pab (ABIN390357) in mouse kidney tissue lysates (35 µg/lane). TBRG1(arrow) was detected using the purified polyclonal antibody (1:60 dilution).
Background publications Tompkins, Hagen, Frazier et al.: "A novel nuclear interactor of ARF and MDM2 (NIAM) that maintains chromosomal stability." in: The Journal of biological chemistry, Vol. 282, Issue 2, pp. 1322-33, 2007 (PubMed).

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