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XPO1 antibody (C-Term)

XPO1 Reactivity: Human IHC (p), FACS Host: Rabbit Polyclonal RB19972 unconjugated
Catalog No. ABIN390636
  • Target See all XPO1 Antibodies
    XPO1 (Exportin 1 (XPO1))
    Binding Specificity
    • 15
    • 10
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 817-846, C-Term
    Reactivity
    • 73
    • 36
    • 35
    • 8
    • 7
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 68
    • 5
    Rabbit
    Clonality
    • 57
    • 16
    Polyclonal
    Conjugate
    • 40
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This XPO1 antibody is un-conjugated
    Application
    • 47
    • 16
    • 15
    • 15
    • 14
    • 14
    • 8
    • 7
    • 6
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
    Predicted Reactivity
    M, Rat
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This XPO1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 817-846 amino acids from the C-terminal region of human XPO1.
    Clone
    RB19972
    Isotype
    Ig Fraction
    Top Product
    Discover our top product XPO1 Primary Antibody
  • Application Notes
    IHC-P: 1:50~100. FC: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Sharma, Åkerström, Sharma, Chow, Teow, Abrenica, Booth, Booth, Mirazimi, Lal: "SARS-CoV 9b protein diffuses into nucleus, undergoes active Crm1 mediated nucleocytoplasmic export and triggers apoptosis when retained in the nucleus." in: PLoS ONE, Vol. 6, Issue 5, pp. e19436, (2011) (PubMed).

  • Target
    XPO1 (Exportin 1 (XPO1))
    Alternative Name
    XPO1 (XPO1 Products)
    Background
    XPO1 mediates leucine-rich nuclear export signal (NES)-dependent protein transport. Exportin 1 specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. This protein also regulates NFAT and AP-1.
    Molecular Weight
    123386
    Gene ID
    7514
    NCBI Accession
    NP_003391
    UniProt
    O14980
    Pathways
    M Phase
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