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HLA Class II DR alpha (HLA-DRA) (AA 149-177), (C-Term) antibody

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Antigen
  • HLA-DRA1
  • MLRW
  • DR-alpha
  • HLA-DRA
  • Mamu-DRA1
Epitope
AA 149-177, C-Term
10
9
8
7
6
5
5
5
4
2
2
1
1
1
1
Reactivity
Human
73
9
9
9
6
5
5
3
2
1
Host
Rabbit
70
30
2
1
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
11
9
3
1
1
1
Application
Flow Cytometry (FACS), Western Blotting (WB)
70
38
20
15
13
9
7
4
3
2
1
1
Supplier
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Immunogen This HLA-DRA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 149-177 AA from the C-terminal region of human HLA-DRA.
Clone RB19527
Isotype Ig
Specificity This HLA-DRA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 156~185 amino acids from the C-terminal region of human HLA-DRA.
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name HLA-DRA (HLA-DRA Antibody Abstract)
Background HLA-DRA is one of the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha and a beta chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages).
Synonyms: HLA class II histocompatibility antigen, DR alpha chain, MHC class II antigen DRA, HLA-DRA1, HLA-DRA
Molecular Weight 28607 DA
Gene ID 3122
UniProt P01903
Research Area Cell Structure, Metabolism
Application Notes WB = 1:1000, FACS = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-HLA Class II DR alpha (HLA-DRA) (AA 149-177), (C-Term) antibody (ABIN390771) Western blot analysis of HLA-DRA Antibody (C-term) (ABIN390771) in HL60 cell line lys...
Flow Cytometry (FACS) image for anti-HLA Class II DR alpha (HLA-DRA) (AA 149-177), (C-Term) antibody (ABIN390771) HLA-DRA Antibody (C-term) (ABIN390771) flow cytometric analysis of HL-60 cells (right...
Background publications De Jager, Jia, Wang et al.: "Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci." in: Nature genetics, Vol. 41, Issue 7, pp. 776-82, 2009 (PubMed).