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Fragile X Mental Retardation 1 (FMR1) (AA 20-48), (N-Term) antibody

Details for Product No. ABIN390866, Supplier: Log in to see
Antigen
  • AT24755
  • BcDNA:GM08679
  • CG6203
  • Dmel\\CG6203
  • EP(3)3517
  • FMR
  • FMR1
  • FMRP
  • FMRp
  • FXR
  • Fmrp
  • cg6203
  • dFMR
  • dFMR1
  • dFMRP
  • dFXR
  • dFXR1
  • dFXRP
  • dFmr1
  • dFmrp
  • dfmr
  • dfmr1
  • dfxr
  • dfxr1
  • dmfr1
  • fmr
  • fmr1
  • FRAXA
  • POF
  • POF1
  • zFMR1
  • Fmr-1
Epitope
AA 20-48, N-Term
25
21
17
13
13
10
4
3
3
3
2
2
1
1
1
1
1
Reactivity
Human, Mouse (Murine)
151
44
42
7
4
3
2
2
2
2
1
Host
Rabbit
67
50
38
1
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
5
5
5
4
4
4
2
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
132
78
42
36
25
13
12
10
7
4
3
3
2
Supplier
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Immunogen This FMR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 20-48 AA from the N-terminal region of human FMR1.
Clone RB20964
Isotype Ig
Specificity This FMR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 27~56 amino acids from the N-terminal region of human FMR1. Note: It was reported by a customer that in addition to the target band, this antibody also recognizes a ~40KD band in mouse cerebellum. This ~40kd band might account for part of the IHC staining in mouse cerebellum.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name FMR1 (FMR1 Antibody Abstract)
Background FMR1 binds RNA and is associated with polysomes. This protein may be involved in mRNA trafficking from the nucleus to the cytoplasm.
Synonyms: Fragile X mental retardation 1 protein, Protein FMR-1, FMRP, FMR1
Molecular Weight 71174 DA
Gene ID 2332
UniProt Q06787
Research Area Signaling, Protein Modifications, Neurology
Application Notes IHC (p) = 1:50-100, WB = 1:1000, FACS = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Immunohistochemistry (IHC) image for anti-Fragile X Mental Retardation 1 (FMR1) (AA 20-48), (N-Term) antibody (ABIN390866) Formalin-fixed and paraffin-embedded human brain tissue reacted with FMR1 Antibody (N...
Western Blotting (WB) image for anti-Fragile X Mental Retardation 1 (FMR1) (AA 20-48), (N-Term) antibody (ABIN390866) Western blot analysis of FMR1 Antibody (N-term) (ABIN390866) in mouse lung tissue lys...
Flow Cytometry (FACS) image for anti-Fragile X Mental Retardation 1 (FMR1) (AA 20-48), (N-Term) antibody (ABIN390866) FMR1 Antibody (N-term) (ABIN390866) flow cytometric analysis of NCI-H460 cells (right...
Background publications Yuhas, Walichiewicz, Pan et al.: "High-risk fragile x screening in Guatemala: use of a new blood spot polymerase chain reaction technique." in: Genetic testing and molecular biomarkers, Vol. 13, Issue 6, pp. 855-9, 2009 (PubMed).