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Details for Product No. ABIN390869

Hydroxyacyl-Coenzyme A Dehydrogenase/3-Ketoacyl-Coenzyme A Thiolase/enoyl-Coenzyme A Hydratase (Trifunctional Protein), alpha Subunit (HADHA) (C-Term), (AA 737-763) antibody

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Antigen
Synonyms ECHA, GBP, HADH, LCEH, LCHAD, MTPA, TP-ALPHA, Mtpa, C77020, RGD1560655, cb1055, hadha, im:7136067, wu:fa14c08
Epitope
»Alternatives C-Term, AA 737-763
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)
Pubmed 1 reference available
Catalog no. ABIN390869
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Immunogen This HADHA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 737-763 AA from the C-terminal region of human HADHA.
Clone RB20987
Isotype Ig
Specificity This HADHA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 734~763 amino acids from the C-terminal region of human HADHA.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name HADHA
Background HADHA is the alpha subunit of the mitochondrial trifunctional protein, which catalyzes the last three steps of mitochondrial beta-oxidation of long chain fatty acids. The mitochondrial membrane-bound heterocomplex is composed of four alpha and four beta subunits, with the alpha subunit catalyzing the 3-hydroxyacyl-CoA dehydrogenase and enoyl-CoA hydratase activities.
Synonyms: Trifunctional enzyme subunit alpha, mitochondrial, TP-alpha, 78 kDa gastrin-binding protein, Long-chain enoyl-CoA hydratase, Long chain 3-hydroxyacyl-CoA dehydrogenase, HADH, HADHA
Pathways: Fatty acid metabolism, beta-Alanine metabolism, Valine, leucine and isoleucine degradation, Tryptophan metabolism, Biosynthesis of unsaturated fatty acids
Molecular Weight 83000 Da
Gene ID 3030
UniProt P40939
Application Notes Recommend dilutions: WB : 1:1000,IHC : 1:10-50,FC : 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Background publications Sims, Brackett, Powell et al.: "The molecular basis of pediatric long chain 3-hydroxyacyl-CoA dehydrogenase deficiency associated with maternal acute fatty liver of pregnancy." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 92, Issue 3, pp. 841-5, 1995 (PubMed).

Alternatives for antigen "Hydroxyacyl-Coenzyme A Dehydrogenase/3-Ketoacyl-Coenzyme A Thiolase/enoyl-Coenzyme A Hydratase (Trifunctional Protein), alpha Subunit (HADHA)", type "Antibodies"
Hosts (22), (1)
Reactivities (23), (17), (14), (12), (12)
Applications (14), (10), (6), (6), (4), (3), (2), (1), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (3), (2), (1)
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