GRB2-Associated Binding Protein 2 (GAB2) (N-Term) antibody
| Antigen |
|
| Synonyms |
KIAA0571, GAB2 |
|
Binding Site
|
|
| Clonality |
Polyclonal |
|
Host
|
|
|
Reactivity
|
|
|
Conjugate
|
Alexa Fluor 350 (5), Alexa Fluor 488 (5), Alexa Fluor 555 (5), Alexa Fluor 647 (5), Biotin (5), Cy3 (5), Cy5 (5), Cy5.5 (5), Cy7 (5), FITC (5), Gold (5), HRP (5), PE (5), PE,Cy3 (5), PE,Cy5 (5), PE,Cy5.5 (5), PE,Cy7 (5)
|
|
Application
|
 Alternatives Western Blotting (WB), Flow Cytometry (FACS), ELISA
|
| Catalog no. |
ABIN390895 |
| Quantity |
0.1 mg (0.25 mg/ml) |
| Price |
280.50 $ Plus shipping costs $45.00
|
|
Bulk discount
|
| Shipping to |
|
| Availability |
Will be delivered in 2 to 3 Business Days |
|
Alternative name
|
GAB2
|
|
Gene ID
|
9846
|
|
UniProt
|
Q9UQC2
|
|
Immunogen
|
This GAB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 9~39 amino acids from the N-terminal region of human GAB2.
|
|
Isotype
|
Ig
|
|
Description
|
Other names: GRB2-associated-binding protein 2, Growth factor receptor bound protein 2-associated protein 2, GRB2-associated binder 2, pp100,KIAA0571, GAB2
|
|
Characteristics
|
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
|
|
Specificity
|
This GAB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 9~39 amino acids from the N-terminal region of human GAB2.
|
|
Molecular Weight
|
74458 DA
|
|
Comments
|
Background: GAB2 is the principal activator of phosphatidylinositol-3 kinase in response to activation of the high affinity IgE receptor.
|
|
Application Notes
|
The suggested dilution is: ELISA ~~ 1:1,000 Western blotting~~ 1:100~500 Flow cytometric~~1:10~50
|
|
Concentration
|
0.25 mg/ml
|
|
Purification
|
Purified
|
|
Buffer
|
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
|
|
Storage
|
Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles
|
|
Research Area
|
Neurology
|
|
Restrictions
|
For Research Use only
|
|
Product
|
Yamasaki, Nishida, Hibi et al.: "Docking protein Gab2 is phosphorylated by ZAP-70 and negatively regulates T cell receptor signaling by recruitment of inhibitory molecules." in: The Journal of biological chemistry, Vol. 276, Issue 48, pp. 45175-83, 2001 (PubMed).
|
Alternatives for antigen "GRB2-Associated Binding Protein 2 (GAB2)", type "Antibodies"
|
Hosts
|
Rabbit (109), Goat (4)
|
|
Reactivities
|
Human (112), Rat (Rattus) (103), Mouse (Murine) (102), Dog (Canine) (19), Cow (Bovine) (18), Horse (Equine) (18), Pig (Porcine) (18)
|
|
Applications
|
Immunofluorescence (IF) (75), Western Blotting (WB) (37), ELISA (32), Flow Cytometry (FACS) (17), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (16), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (15), Immunoprecipitation (IP) (7), Immunohistochemistry (IHC) (6), Immunoelectron Microscopy (IEM) (5), Immunocytochemistry (ICC) (1)
|
|
Conjugates
|
Alexa Fluor 350 (5), Alexa Fluor 488 (5), Alexa Fluor 555 (5), Alexa Fluor 647 (5), Biotin (5), Cy3 (5), Cy5 (5), Cy5.5 (5), Cy7 (5), FITC (5), Gold (5), HRP (5), PE (5), PE,Cy3 (5), PE,Cy5 (5), PE,Cy5.5 (5), PE,Cy7 (5)
|
|
Epitopes
|
pSer623 (37), pTyr452 (19), pTyr643 (19), Internal Region (5), C-Term (4), AA 285-676 (1), N-Term (1), N-Term,AA 9-39 (1)
|
