SRP72 antibody (Signal Recognition Particle 72kDa) (AA 119-148)

Details for Product anti-SRP72 Antibody No. ABIN390903, Supplier: Log in to see
Antigen
  • CG5434
  • Dmel\\CG5434
  • wu:fi03d11
  • 5730576P14Rik
  • 72kDa
  • AI132477
  • BC019196
  • C77589
  • BMFF
  • Signal recognition particle protein 72
  • signal recognition particle 72kDa
  • signal recognition particle subunit Srp72
  • part of the signal recognition particle (SRP) ribonucleoprotein (RNP) complex
  • type II secretory pathway family
  • signal recognition particle 72
  • Srp72
  • SRP72
  • srp72
Epitope
AA 119-148, Center
14
9
3
3
1
1
Reactivity
Human
24
4
4
3
3
3
2
2
2
2
2
1
1
1
Host
Rabbit
24
Clonality (Clone)
Polyclonal ()
Conjugate
This SRP72 antibody is un-conjugated
2
2
2
2
2
2
Application
Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
23
17
14
6
5
4
1
1
1
Options
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Immunogen This SRP72 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 119-148 AA from the Central region of human SRP72.
Clone RB21267
Isotype Ig
Specificity This SRP72 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 126~156 amino acids from the Center region of human SRP72.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name SRP72 (SRP72 Antibody Abstract)
Background Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. It binds the 7S RNA only in presence of SRP68. This ribonucleoprotein complex might interact directly with the docking protein in the ER membrane and possibly participate in the elongation arrest function.
Synonyms: Signal recognition particle 72 kDa protein, SRP72, SRP72
Molecular Weight 74606 DA
Gene ID 6731
UniProt O76094
Research Area Signaling, Protein Modifications, Neurology
Application Notes FACS = 1:10-50, WB = 1:1000, IHC (p) = 1:50-100, IF = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-SRP72 antibody (Signal Recognition Particle 72kDa) (AA 119-148) (ABIN390903) Western blot analysis of SRP72 Antibody (Center) (ABIN390903) in Hela cell line lysat...
Immunohistochemistry (IHC) image for anti-SRP72 antibody (Signal Recognition Particle 72kDa) (AA 119-148) (ABIN390903) Formalin-fixed and paraffin-embedded human pancreas with SRP72 Antibody (Center), whi...
Background publications Utz, Hottelet, Le, Kim, Geiger, van Venrooij, Anderson: "The 72-kDa component of signal recognition particle is cleaved during apoptosis." in: The Journal of biological chemistry, Vol. 273, Issue 52, pp. 35362-70, 1999 (PubMed).