Forkhead Box A3 (FOXA3) (C-Term) antibody

Antigen: Forkhead Box A3 (FOXA3)

Synonyms: FKHH3, HNF3G, TCF3G, MGC10179, Hnf3g, Tcf3g, Hnf-3g, Tcf-3g, fkd2, Zffkh1, fa11c04, zf-FKH1, forkhead-2, wu:fa11c04, wu:fc37a08, FOXA3, HNF3-G

Binding Site: C-Term

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Application: Western Blotting (WB), ELISA

Certificates: ISO 9001:2008

Catalog no.: ABIN390933

Additional Information

Alternative name: FOXA3

Gene ID: 3171

UniProt: P55318

Immunogen: This FOXA3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 273~303 amino acids from the C-terminal region of human FOXA3.

Isotype: Ig

Description: Other names: Hepatocyte nuclear factor 3-gamma, HNF-3-gamma, HNF-3G, Forkhead box protein A3, Fork head-related protein FKH H3, TCF3G,HNF3G, FOXA3

Characteristics: Purified Rabbit Polyclonal Antibody (Pab)

Specificity: This FOXA3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 273~303 amino acids from the C-terminal region of human FOXA3.

Molecular Weight: 37140 DA

Comments:

Background: FOXA3 is a transcription activator for a number of liver genes such as AFP, albumin, tyrosine aminotransferase, PEPCK, etc. Interacts with the cis-acting regulatory regions of these genes.

Application Details

Application Notes: The suggested dilution is: ELISA ~~ 1:1,000 Western blotting~~ 1:50~100

Concentration: 0.25 mg/ml

Purification: Purified

Buffer: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Storage: Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles

Research Area: Transcription Factors, Signaling, Neurology, Cell Structure

Restrictions: For Research Use only

Images

Western blot analysis of FOXA3 Antibody (C-term) (ABIN390933) in HL-60 cell line lysates (35ug/lane). FOXA3 (arrow) was detected using the purified Pab.

Publications

Product: Birrane, Soni, Ladias: "Structural basis for DNA recognition by the human PAX3 homeodomain." in: Biochemistry, Vol. 48, Issue 6, pp. 1148-55, 2009 (PubMed).